embryonal carcinoma


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Related to embryonal carcinoma: Yolk sac tumor
  • noun

Words related to embryonal carcinoma

malignant neoplasm of the testis

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The factors that best predicted relapse were vascular channel invasion first of all and then predominance of embryonal carcinoma on histology.
The other mimicker is the tubular variant of seminoma, in which the tumor architecture resembles gland-forming embryonal carcinoma yet retains the cytologic features of seminoma (Figure 1, B).
Embryonal carcinoma cells derive from teratocarcinomas, or embryonic cancers.
Histological examination revealed a mixed germ cell tumour containing primarily a yolk sac component (85%), as well as sarcoma (sarcomatous) component (10%), embryonal carcinoma (4%) and mature teratoma (1%) components.
21-22) The histologic classification of GCTs at this site is identical to that used in the gonads: seminomatous (pure), nonseminomatous (yolk sac tumor, embryonal carcinoma, choriocarcinoma, and mixed GCTs), and teratomas.
Most commonly reported neoplasms are embryonal carcinoma, germ cell tumor and seminomas.
30) CD30 stains most embryonal carcinomas and can be used as part of a panel of markers to distinguish metastatic embryonal carcinoma from somatic carcinoma.
These included 3 metastatic melanomas, 3 EAs, 4 epithelioid hemangiomas of soft tissue, 3 epithelioid mesotheliomas, and 10 metastatic carcinomas with epithelioid morphology (3 RCCs, 2 poorly differentiated carcinomas of unknown primary, and 1 each of gastric signet ring carcinoma, embryonal carcinoma, squamous carcinoma, lung adenocarcinoma, and colonic adenocarcinoma).
Cells with vesicular nucleus resembling embryonal carcinoma, bizarre giant cells, areas of necrosis, and frequent mitosis, including abnormal forms and blood vessel invasion, are also seen.
About 50% of gonadoblastomas display overgrowth by dysgerminoma, and in an additional 10%, other malignant germ cell-tumor components, such as immature teratoma, embryonal carcinoma, choriocarcinoma, or yolk sac tumors can be appreciated.
CD30 and c-Kit (CD117) used in combination are known to be useful to distinguish between embryonal carcinoma and seminoma in the gonads.
3) Although intratubular embryonal carcinoma has been described adjacent to invasive embryonal carcinoma, to the best of our knowledge it has not been reported as an isolated finding in human testis.
Granulosa cell tumors elevate inhibin levels while embryonal carcinomas increase AFP and HCG.
Occasionally, germ cell tumors of the testis such as seminomas, embryonal carcinomas, and intratubular germ cell tumors may be considered in the differential diagnosis when the tumor is infiltrating into the testicular parenchyma.