pump (mefA gene) is the most common in Spain.
species such as wheat, a rapid and consistent malate efflux
The MFS Efflux
Proteins of Gram-Positive and Gram-Negative Bacteria (Massoud Saidijam, Kim E.
Reduced ABCB1 activity by psoralen as shown by rhodamin-123 efflux
in a mature spruce forest in Southern Germany.
The researchers suggested that adding this currently approved drug to TB therapy, or working to develop drugs that more specifically block the bacterial efflux
pumps in TB organisms, might reduce multi-drug tolerance.
Antibiotics and inhibitors: Rifampicin, isoniazid, ethambutol, streptomycin, oloxacin, norloxacin, kanamycin and efflux
pump inhibitors carbonyl cyanide m-chlorophenylhydrazone (CCCP) and verapamil were obtained from Sigma, USA.
A critical part of RCT is cholesterol efflux
, in which accumulated cholesterol is removed from macrophages.
Cells naturally resist toxicants through multidrug/multixenobiotic resistance (MDR/MXR) efflux
transporters, proteins that keep foreign chemicals from entering cells.
The initial compound is not active against certain gram-negative pathogens such as- Pseudomonas and Escherichia coli that have efflux
mechanisms capable of disabling it.
Have the researchers considered the possibility of such a response triggering the formation of efflux
pumps, either specific to the triggering "foreign" body or to a group of bodies similar to the cow pox-small pox link?
When the product of the electrochemical potential and zF is negative, cations and anions are accumulated passively (spontaneously) and efflux
The focus of these presentations is to highlight the importance of basolateral efflux
in determining hepatotoxicity as well as in controlling intracellular concentrations of both endogenous and exogenous compounds.
ZnT8 is a member of the large cation efflux
family and is one of the major targets of type 1 diabetes autoimmunity.
Numerous resistance mechanisms have been identified including antibiotic inactivation, target-based mutation compromising drug binding, reduced permeability and efflux
mechanisms that pump the drugs out.