Table 1: Distribution of cases in relation to age and gender Age in Years Males Females Total <9 4 3 7 10-19 7 5 12 20-29 8 9 17 30-39 11 12 23 40-49 10 8 18 50 & Above 5 4 9 Total 45 41 86 Table 2: Drugs causing fixed drug eruptions
They were also reassured of the relative safety of provocation tests in fixed drug eruption
Key words Cefuroxime, congenital, fixed drug eruption
03 Lichenoid eruptions 1 Lichenoid drug eruption
Conclusion Frequency distribution of the offending drugs and the adverse reactions revealed that cephradine was responsible for maculopapular rash, sulphonamides for Stevens-Johnson syndrome, indigenous medicines for exfoliative dermatitis, NSAIDs for urticaria and paracetamol for fixed drug eruption
Biopsy of the lichenoid drug eruption
from the sole confirmed our diagnosis of lichenoid drug eruption
In our case, the clinical findings and the temporal association with the drug intake and the patient's history established Azithromycin to be the culprit in causing the Fixed Drug Eruption
4-6] Almost any medicine can induce skin reactions, and certain drug classes, such as non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics and antiepileptics have drug eruption
rates approaching 1-5%.
2) Cutaneous lesions of fixed drug eruption
start as a solitary erythematous macule that subsequently evolves into an edematous plaque.
He was diagnosed as drug eruption
in a local hospital and received irregular corticosteroids therapy for two weeks.
Fixed drug eruption
(FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug.
This scenario was illustrated by recent reports of a mysterious fixed drug eruption
attributed to Baczol, a cold and flu remedy available over the counter in El Salvador for upper respiratory infections.
In phototoxic reaction, distribution includes only sun-exposed skin and clinical characteristics are similar to exaggerated sunburn, whereas photoallergic reaction includes dermatitis (systemic administration of photo-allergen causes a picture of drug eruption
, while topical application of the substance causes eczematous morphology) (4-10).
The common morphologic patterns observed during various studies are exanthematous rashes, urticarial rashes, fixed drug eruption
and erythema multiforme.
Generalized lichenoid drug eruption
associated with imatinib mesylate therapy.