is currently approved by the FDA for use in 14 different cancer types.
This study shows that patients treated with PM1183 in combination with doxorubicin
(Phase I/II clinical trial) reached a progression free survival (5.
In this study, we aimed to investigate the efficacy of salinomycin in the treatment of cholangiocarcinoma, and to determine if it could reverse chemoresistance to doxorubicin
Dr Reddy's Laboratories Ltd (NSE: DRREDDY), one of India's largest multinational pharmaceutical companies, announced on Wednesday that it has received approval from the US Food and Drug Administration (FDA) to launch its doxorubicin
hydrochloride liposome injection in the US market.
Each animal was treated with normal saline 1ml intraperitoneal in group A, doxorubicin
alone in group B and doxorubicin
+ vitamin C in group C.
Animals in group G2 received 1mg/kg of doxorubicin
twice a week for six weeks, and animals in group G1 received only saline solution twice a week for six weeks.
This research studies the protective effect of selenium and zinc oxide nanoparticles on reproduction system, fertility, tissue changes in uterus and ovary of mature female rats after treatment with doxorubicin
2] A long-acting form of doxorubicin
encapsulated in liposomes has been marketed since the mid-1990s for the treatment of various malignancies.
Blum, "Comparison of cardiac events associated with liposomal doxorubicin
, epirubicin and doxorubicin
in breast cancer: a Bayesian network meta-analysis," European Journal of Cancer, vol.
Then, we investigated whether they could sensitize P388 cells overexpressing P-glycoprotein to doxorubicin
and vinblastine treatment and, thereby, overcome multidrug resistance.
produced severe cardiotoxicity confirmed by markedly raised serum levels of cTnI CK- MB LDH and grade 3 necrosis of the heart tissue in rabbits.
analogs that are less cardiotoxic (cause reduced in vivo chronic cardiotoxicity in rats and rabbits) are also less potent as poisons for topoisomerase 2[beta] (top2[beta]) and equally or more potent as poisons for topoisomerase 2a (top2[alpha]) compared to doxorubicin
HCL liposome injection is used to treat patients with ovarian cancer that has progressed or recurred after platinum-based chemotherapy.
London, October 29 ( ANI ): Doxorubicin
, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumours, in some patients.
Doxophos Vet, which is Oasmia's second drug candidate within the animal health segment, is a novel formulation of doxorubicin