Thus, it appears to us that, except for cases in which imaging studies show reticulation on HRCT, only restrictive or mixed restrictive/obstructive patterns, or (less certainly) a markedly reduced diffusing capacity
in the absence of evidence of significant airflow obstruction, allow the diagnosis of RBILD.
Studies have shown that sea-level natives, or lowlanders, exhibit no change in diffusing capacity after living four weeks at high altitude (12,000 feet).
Interestingly, it has been shown that natives of 16,000 feet have significantly higher diffusing capacity than natives of 12,000 feet.
Pulmonary function, diffusing capacity
, and inflammation in healthy and asthmatic subjects exposed te ultrafine particles.
Therefore, the overall conductance, transfer factor or diffusing capacity
of lung is a function of Dm or membrane conductance, which is the ability of the lung's surface area to transfer oxygen and [theta]Qc which is the ability of the lung's perfusion to remove oxygen.
His pulmonologist repeated lung function tests, which showed a further decline in diffusing capacity
to 44% predicted (Table 1), and a thin-section computed tomography (CT) scan of the chest (Figure 3) showed "ground glass" opacities indicating interstitial lung disease and mild bronchiectasis.
today announced that it has introduced an FDA-listed nitric oxide gas product (NO-Diff (TM) Nitric Oxide 800 ppm Lung Diffusion Mixture) for use in membrane diffusing capacity
(DLNO) testing in pulmonary function laboratories in the U.
Spirometry results, lung volumes, and measures of carbon monoxide diffusing capacity
had been normal in 13 of the soldiers, while another 19 had shown only isolated low carbon monoxide diffusing capacity
Chapter 5 is dedicated to Diffusing Capacity
Tests and does an excellent job at clearly illuminating an otherwise confusing subject.
Pulmonary function testing revealed reduced lung volumes, including forced ventilatory capacity (46% of predicted), forced expiratory volume in 1 sec (54% of predicted), total lung capacity (53% of predicted), functional residual capacity (43% of predicted), and carbon monoxide diffusing capacity
(36% of predicted).
A diffusing capacity
of the lungs for carbon monoxide (DLCO) corrected for hemoglobin (HgB) of 30-79 percent of predicted normal and a FVC of greater than 50 percent of predicted normal were also required for enrollment.
The diffusing capacity
for carbon monoxide has fairly reliable predictive value of survival at baseline with patients under 40% of predicted having worse outcomes.
In our lab, for example, we use a diffusing capacity
simulator rather than biocontrols to track DLCO.
After the initial 1 week of 20 mg prednisone bid (twice per day), the patient's symptoms had completely subsided, her lung crackles had cleared, and her diffusing capacity
had increased from 45% predicted to 71% predicted (6 December 2000).
The topics explored in the book include spirometry, lung volumes, diffusing capacity
and blood gases, according to Mr.