Our lead product candidate Resunab is a novel oral anti-inflammatory drug scheduled to commence Phase 2 clinical trials for the treatment of cystic fibrosis and diffuse scleroderma
Anti-Scl70 and anti-RNA polymerase III results are positive in 20% to 30% of patients with diffuse scleroderma
but are seldom positive in those with CREST syndrome.
NEW ORLEANS -- Women with diffuse scleroderma
, including those with a previous renal crisis, should delay pregnancy until their disease has stabilized, Dr.
One notable exception is patients with diffuse scleroderma
disease of less than 4 years' duration.
Systemic scleroderma can be classified into two forms, depending on the degree of skin involvement: limited scleroderma - often referred to as CREST - and diffuse scleroderma
The nucleolar ANA pattern is common in patients with diffuse scleroderma
and the centromere pattern for CREST syndrome.
Daval's Clinical and Scientific Director, Professor Syed Haq commented, "This study, conducted at one of the world's leading scleroderma centres, was an important first step towards understanding whether AIMSPRO could significantly help patients with diffuse scleroderma
and potential overlapping connective tissue disorders, for which there is no cure, by arresting the disease even in its latter stages.
As a result, Connetics will not pursue the further development of relaxin for the treatment of diffuse scleroderma
The purpose of the trial was to evaluate the safety, efficacy and dose response of relaxin in treating diffuse scleroderma