Cardella E Insulin therapy during diabetic ketoacidosis
A 49 year old male presented with the clinical features of a severe left upper lobe (LUL) community acquired pneumonia, acute renal failure, diabetic ketoacidosis
with a pH on admission of 6.
Deaths associated with diabetic ketoacidosis
and hyperosmolar coma 1973-88.
is a condition of excessively high blood sugar level that leads to formation of chemical substances called ketone bodies.
Cases include ectopic pregnancy, septic abortion, hypertensive emergencies, cardiac failure, acute asthma attack, fetal distress, jaundice, obstructed labor, postpartum collapse, acute pelvic inflammatory disease, ovarian torsion, endotoxic shock, acute urinary retention, sexual assault, abnormal uterine bleeding, emergency contraception, gynecologic oncology emergencies, postexposure prophylaxis to HIV and hepatitis B, cardiopulmonary resuscitation, diabetic ketoacidosis
, and medicolegal and ethical issues.
Type 1 diabetics who have brittle diabetes or those with poor control are advised not to fast, as well as those with low blood sugar (hypoglycemia) unawareness, frequent low and high blood sugar, severe kidney and eye complications, poorly controlled hypertension, or unstable angina, and those prone to frequent diabetic ketoacidosis
, as they are at high risk of developing severe complications.
More than 1,500 children in Wales have Type 1 diabetes, which, if left untreated, can lead to diabetic ketoacidosis
, dangerously high blood glucose levels that can lead to coma or death.
(DKA) can occur in the presence of partial or temporary insulin deficiency, and therefore cannot be relied on as an absolute indicator that the patient has type 1 diabetes or that long-term insulin therapy will be required.
If children are not diagnosed at this stage, they can proceed to a more dangerous stage called diabetic ketoacidosis
, which is characterized by vomiting, abdominal pain and dehydration, and may lead to a state of coma.
Linagliptin/metformin HCl are not for the treatment of Type 1 Diabetes or diabetic ketoacidosis
(increased ketones in the blood or urine).
The most serious complication of both HHS and diabetic ketoacidosis
are cerebral edema and acute respiratory distress syndrome (7).
occurs in diabetics when the body cannot use sugar (glucose) as a fuel source due to an insulin deficiency and uses fat as fuel instead.
This is one of the reasons why a quarter of children with Type 1 diabetes are only diagnosed once they are already seriously ill with diabetic ketoacidosis
, a life-threatening condition that needs immediate treatment in hospital.
Mostly seen in hypothermia but they may be associated with sepsis, hypokalaemia, hypercalcemia, hypoglycemia, diabetic ketoacidosis
, neuroleptic drug abuse, Brugada syndrome, damage to brain and ischemic heart disease (2-4).
Untreated, Type 1 diabetes can result in serious health problems such as diabetic ketoacidosis
, which can lead to a potentially fatal coma.