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A controlled trial of desipramine in 18 men with posttraumatic stress disorder.
SAMe consistently performs as well as or better than older-generation antidepressants such as imipramine and desipramine, drugs which are highly effective but have an unfavorable safety profile.
In this experiment, the mice were divided into six groups in six cages, including control group, desipramine group, YZ-30 group, YZ-50 group, YZ-70 group and YZ-95 group.
In human patients with a type of depression called melancholic depression, fluoxetine/Prozac doesn't work as an antidepressant but desipramine does work.
Chronic desipramine and fluoxetine differentially affect extracellular dopamine in the rat prefrontal cortex.
2) Three randomized, controlled trials have reported modest beneficial effects from short-term treatment with desipramine, (3) sertraline or cognitive behavioural therapy (4) and paroxetine.
Routinely used TCAs include protriptyline, desipramine, and imipramine.
Despite their success rate, these still fail in 25% of cases, and may have many unwanted side effects (such as tics), forcing a search for second line agents such as drugs that affect the noradrenalin and serotonin systems, noradrenalin reuptake inhibitor desipramine and others.
The possible roles of these two major pathways in regulation of the hematopoiesis processes were examined by using pharmacological agents such as desipramine and 6-OHDA in order to determine their effects on the hematological parameters.
The effect of setraline on the pharmacokinetics of desipramine and imipramine.
The circulating neurotransmitters noradrenaline, adrenaline, dopamine, platelet serotonin, plasma serotonin, and tryptophan were assessed before and after a desipramine challenge (10 mg injected intramuscularly) in patients affected by neural sympathetic predominance (N), adrenal sympathetic predominance (A), and normal controls (C).
The addition of desipramine to buprenorphine or methadone may augment or facilitate abstinence from cocaine and opioids in patients dependent on both substances (Kosten et al.
One category includes tricyclic antidepressants, such as imipramine (Tofranil), desipramine (Norpramin), clomipramine (Anafranil) and protriptyline (Vivactil).
She has been on Synthroid 125mcg for hypothyroidism; long-acting carbamazepine 1200mg daily for her seizures; long-acting lithium 900mg daily; sertraline 200mg daily; desipramine 100mg daily; lorazepam 1.
The administration of hypertonic sodium chloride to rats with desipramine toxicity has been shown to be as effective as sodium bicarbonate in reversing QRS prolongation and hypotension (8).
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