Auto-immune blistering diseases include pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, dermatitis herpetiformis
, and linear IgA dermatosis.
They are both blistering diseases and on immunofluorescence microscopy show evidence of IgA deposition; however, dermatitis herpetiformis
is associated with a gluten-sensitive enteropathy (coeliac disease).
27) , 1998 Dermatitis herpetiformis
Chorzelski and Jablonska (29), 1975; Egan et al.
Adults exhibit fewer digestive disorders than children, and some of these symptoms include fatigue, arthritis, depression, tingling and numbness in the hands and feet, and a skin rash called dermatitis herpetiformis
(DH) (Celiac Disease Foundation, 2014b).
To be eligible, patients must have a clinically confirmed diagnosis of coeliac disease or dermatitis herpetiformis
, live in Scotland and be registered as an NHS patient with a GP practice.
Celiac disease patients might present with recurrent oral ulcers and dermatitis herpetiformis
is also quite common in such patients.
But when I realised that I would get rid of a lot of these health niggles - the skin rash (called dermatitis herpetiformis
, linked to coeliac disease), the horrible headaches, the tummy upsets, the tiredness - all by changing my food habits, it was very motivating.
3,8,13) Other possible non-GI symptoms include abnormal liver function test results and skin disorders such as dermatitis herpetiformis
, a pruritic rash with cutaneous IgA deposits.
When a person with Celiac Disease eats wheat, rye or barley, the gluten causes the immune system to damage the lining of the small intestine thus causing stomach pain, diarrhea, fatigue, joint pain and a skin condition called dermatitis herpetiformis
characterized by itchy skin rashes.
While type 3 groups comprises with autoimmune thyroid disease, myasthenia gravis, thymoma, Sjogren's syndrome, pernicious anemia, idiopathic thrombocytopenic purpura (ITP), Addison's disease, diabetes, vitiligo, autoimmune hemolytic anemia, systemic lupus erythematosus (SLE) and dermatitis herpetiformis
A severe type of skin rash, called dermatitis herpetiformis
Features that may indicate a diagnosis of coeliac disease (adapted from NICE, 2009; Steele, 2011; Paul et al, 2010; Barnard et al, 2010; Karpati, 2012) * Abdominal bloating and pain * Anaemia * Behaviour changes * Bone pain * Concentration difficulties (may present with a fall in 'grades' at school) * Delayed growth * Delay in onset of puberty * Dermatitis herpetiformis
(may be persistent and resistant to treatment in absence of GFD) * Diarrhoea * Failure to thrive (may show fall in centiles) * Fatigue * Flatulence * Mouth: pale-coloured sores (aphthous ulcers) * Stools: pale in colour and foul-smelling (tends to float in toilet pan, difficult to flush) * Teeth: discoloration or loss of enamel
People with Celiac Disease often suffer from gas, bloating, diarrhea and a skin condition known as dermatitis herpetiformis
Others include dermatitis herpetiformis
, identified by an itchy rash, and the neurological condition gluten ataxia.
Some CD patients additionally suffer from Duhring's dermatitis herpetiformis
, a recurrent skin disease characterized by subepidermal blisters.