Melanoma associated leukoderma is a rare disease characterized by hypopigmented or depigmented
macules, which are usualy localized at distant sites from the primary malignant melonoma.
Speciic indings include trismus, stiff and small tongue, blanched and leathery floor of mouth, fibrotic and depigmented
gingiva, rubbery soft palate with decreased mobility, blanched and atrophic tonsils, shrunken band like uvula and sinking of cheek not commensurate with age or nutritional status.
Bands of discoloured or depigmented
hair are often red flags for severe nutritional deficiencies in protein or iron.
Carapace with front edge densely pigmented; ocular tubercle black, with a dark stripe from postocular furrow to lateral ocelli, leaving an anterior depigmented
triangle that only in very pigmented specimens is pigmented; lateral surface with dark reticulated pigment; with 2 posterolateral dark spots.
Northern populations became depigmented
fast," explains Hollis, because the mutation that led to lighter skin had a huge survival advantage.
Vitiligo: a hypopigmentation condition that creates smooth, depigmented
white spots on the skin that vary in size and location.
Stage I disease is characterized by ankle edema without trophic changes, stage II by edema plus hyperpigmented or depigmented
areas and indurations, and stage III by open or healed leg ulcers.
A VITILIGO is a distressing condition which causes patches of depigmented
(very pale) skin and hair.
Mucocutaneous manifestations of secondary syphilis * Coppery red, asymptomatic, generalized maculopapular lesions * Split papules (especially at corners of lips or foreskin) * Psoriasiform patches on palms and soles * Moist, hypertrophic, coalescing papules in perineum (condyloma lata) * Depigmented
macules on a hyperpigmented background (back or sides of neck) * Alopecia (may be patchy ["moth-eaten"] or diffuse) * Oval mucous patches in mouth (palate, tongue, mucosa) or vaginal introitus Table 3.
Approximately 2 weeks after onset of nonspecific symptoms, pustules form scabs, which then become depressed and depigmented
Skurkovich concluded by stating, "That in a pilot study for this disease, four weeks after a short-course of therapy, patients developed thin depigmented
Poliosis is the term used to describe a localized area of hypopigmented or depigmented
The clinical diagnosis is based upon a finding of multifocal choroidal depigmented
lesions (usually with some associated pigmentation at their margin) (Figure 5), peripapillary atrophy, and in more advanced cacus, a macular choroidal neovascular membrane.