On cutaneous examination, there were multiple hyperpigmented, hypopigmented and depigmented
macules of size ranging from 1 mm to 15 mm involving trunk, buttocks, arms and forearms, thighs and legs sparing face, palms, soles, hands, feet, nails, teeth and mucosa (Figure 2).
In the NCMT group 25 patients were enrolled with 125 unresponsive depigmented
sites, 5 patients for vitiligo, 5 patients for postherpetic depigmentation, 5 patients for frictional depigmentation, 5 patients for contact depigmentation and 5 patients for Nevus depigmentation.
Vitiligo is an acquired pigmentation disorder characterized by depigmented
patches as a result of the disappearance of functioning melanocytes from the epidermis.
22 Trichrome vitiligo is also a rare type represents a tan zone of varying width between normal and depigmented
Ultrastructural study of linear verrucous and depigmented
A full mucocutaneous examination showed no abnormality except the depigmented
patches as mentioned above.
Mucosal areas of mouth, nose and the retina may be affected and the hairs on depigmented
skin may also be affected (poliosis).
This is an umbrella term inclusive of conditions wherein the affected hairs undergo an abrupt conversion from anagen to telogen (anagen release), clinically seen as localized shedding of hair in the telogen and morphologically identified as hair with a depigmented
Lips had dry, erythematous and depigmented
Less keratinocyte-derived factors related to more keratinocyte apoptosis in depigmented
than normally pigmented suction-blistered epidermis may cause passive melanocyte death in vitiligo.
The lesions are discrete or confluent and appear as discolored or depigmented
areas of the skin.
A 16-year-old male patient with asymptomatic, multiple, depigmented
patches over both the knees, elbows, shins, lips, palms, distal parts of the digits and feet for five years presented to our outpatient department with red, elevated, scaly lesions which had developed over the last one year.
Case 1: A 14years old boy (brother) came to skin OPD and presented with history of hemorrhagic bullous lesions over the body parts exposed to trauma since infancy and these lesions were leaving depigmented
atrophic scars after rupturing.
The central parts of some of these lesions were completely depigmented
Ash leaf spots were seen on the forehead of the child as depigmented