deoxyguanosine


Also found in: Dictionary, Medical, Wikipedia.
  • noun

Synonyms for deoxyguanosine

a nucleoside component of DNA

Synonyms

Related Words

References in periodicals archive ?
For example, the first G peak is twice as tall as the first T peak, indicating that 2 consecutive deoxyguanosine triphosphates (underlined) were incorporated, whereas only one deoxythymidine triphosphate (underlined) was incorporated; 1X and 2X lines represent peak heights because of single or double base incorporation events, respectively.
Mitochondrial DNA depletion syndrome (MDS), characterized by a reduction in mtDNA copy number, has been linked to mutations in the thymidine kinase 2 (TK2) and deoxyguanosine kinase genes (20).
DEOXYGUANOSINE ADDUCT FORMATION OF 2-HYDROXY-1,4-DIOXANE
5 mg/kg to 3 mg/kg were well-tolerated among the broad spectrum of safety parameters being monitored Additionally, BCX-4208 achieved a dose-related inhibition of PNP, which effectively increases the serum level of deoxyguanosine that is necessary for selective suppression of T-cell activation.
Previously S-[1-(N2 deoxyguanosinyl)methyl]GSH had been identified as the major adduct formed by GSCH2OAc and deoxyguanosine.
8-OHdG is a by-product from damaged DNA when it is attacked by hydroxyl free radicals at deoxyguanosine in DNA (Park and Floyd 1992).
Carbovir triphosphate inhibits the activity of HIV reverse transcriptase (RT) both by competing with a natural substrate deoxyguanosine 5'-triphosphate and by being incorporated into nascent viral DNA, resulting in the termination of replication (Epzicom Highlights of Prescribing Information, 2012).
Depletion and multiple deletions of mtDNA caused by mutational change in adenine nucleotide translocator (ANT1 [SLC25A4]), thymidine phosphorylase (ECGF1 [TYMP]), mitochondrial thymidine kinase (TK2), deoxyguanosine kinase (DGUOK), succinyl-coenzyme A ligase (adenosine 5'-diphosphate-forming) subunit b (SUCLA2), succinylCoA ligase (GDP-forming) subunit alpha (SUCLG1), optic atrophy 1 protein (OPA1), p53-inducible ribonucleotide reductase (RRM2B), and the mitochondrial inner membrane protein MPV17 have been reported in similar clinical syndromes.
The focus of this research was to study 2-hydroxy-1,4-dioxane, a by-product of [alpha]-hydroxy-N-nitrosomorpholine, and to determine its effect on deoxyguanosine (dG).
deoxynucleotide triphosphates (dNTPs), which are the nucleotides deoxyadenosine triphosphate (dATP), deoxyguanosine triphosphate (dGTP), deoxycytidine triphosphate (dCTP), and deoxythymidine triphosphate (dTTP) that compose DNA.
At the present time, mutations in at least 9 genes [POLG, [4] polymerase (DNA directed), gamma; DGUOK, deoxyguanosine kinase; TK2, thymidine kinase, mitochondrial; TYMP, thymidine phosphorylase; MPV17, MpV17 mitochondrial inner membrane protein; SUCLA2, succinate-CoA ligase, ADP-forming, beta subunit; SUCLG1, succinate-CoA ligase, alpha sub unit; RRM2B, ribonucleotide reductase M2 B (TP53 inducible); C10orf2, chromosome 10 open reading frame 2 (also known as TWINKLE)] have been found to cause mtDNA depletion (3-17).
5 mM magnesium chloride, 200 [micro] Meachof deoxyadenosine triphosphate, deoxycytidine triphosphate, deoxyguanosine triphosphate, and thymidine monophosphate.
The biomarker 8-hydroxy-2-deoxyguanosine (8-OHdG) is an oxidized metabolite of deoxyguanosine excreted after digestion of DNA repairing enzyme.
8-OHdG: (8-oxo-2'-deoxyguanosine) is an oxidized derivative of deoxyguanosine.
Fluorescein-labeled oligonucleotides for real-time PCR: using the inherent quenching of deoxyguanosine nucleotides.