deoxycytidine

Takeda K, Kurata N, Kuwabara T, Kobayashi S, Fukuoka M (1998) Interleukin 6 is a cause of flu-like symptoms in treatment with a deoxycytidine analogue.

coli strain (S05218) that, upon the expression of the human deoxycytidine kinase (DCK) gene, exhibited reduced relative growth in the presence of Ara-C in minimal growth medium.

Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.

High incidence of alternatively spliced forms of deoxycytidine kinase in patients with resistant acute myeloid leukemia.

SAHA also potentiated the effects of 5-Aza-2' Deoxycytidine on a CTCL cell line.

5 mmol/L magnesium chloride (Perkin-Elmer); 200 pmol/L each of deoxyadenosine triphosphate, deoxycytidine triphosphate, deoxyguanosine triphosphate, and deoxythymidine triphosphate (Sigma); 200 pmol of each primer; and 10 [micro]L of the extracted DNA sample.

There are three classes of anticancer agents on the market that are analogous to CYC682: fluorouracil analogs, like capecitabine and 5-FU; 2 deoxycytidine analogs, like cytarabine and gemcitabine, the market leading nucleoside analogue; and purine analogs, like 6-mercaptopurine.

5 mM each deoxydenosine 5'-triphosphate (TP), deoxycytidine TP, deoxyguanosine TP, and deoxythymidine TP] at 42[degrees]C for 1 hr.

1% Triton X-100 (Nacalai Tesque, Kyoto, Japan); 2% formamide; 10 pmol of primer pairs; 200 [micro]mol each of deoxyadenosine triphosphate, deoxyguanosine triphosphate, deoxycytidine triphosphate, and deoxythymidine triphosphate; and 2.

Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues [Review].

CYC682 maybe particularly active in tumours with a low ratio of cytidine deaminase to deoxycytidine kinase, two enzymes involved in inactivating and activating respectively the mechanism by which CYC682 acts.

The amplification solution consisted of the following: 1 [micro]mol/L of each consensus primer; 200 [micro]mol/L each of deoxyadenosine triphosphate, deoxycytidine triphosphate, and deoxyguanosine triphosphate; and 140 [micro]mol/L of deoxythymidine triphosphate.

Human Deoxycytidine Kinase 2 WO96/21724 18-Jul-1996 51.

In the absence of Vif, CEM15 alters the chemical composition of deoxycytidine, a constituent of viral DNA, thereby disabling viral replication and stopping the spread of HIV.

Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues.