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  • adj

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not as far along as normal in development

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Wynn and Wynn (34) stressed the importance of women taking folic acid supplements before conception because estradiol and progesterone--both necessary for optimal maturation of the oocyte--are depressed by inadequate folate or vitamin B12 intake and induce long follicular phases or delayed ovulation, both of which are markers for slow down in embryonic growth and risk of congenital anomalies (34).
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