delavirdine


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Synonyms for delavirdine

a non-nucleoside reverse transcriptase inhibitor (trade name Rescriptor) used to treat AIDS and HIV

References in periodicals archive ?
Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles.
The parent study was a randomized, double-blind clinical trial of delavirdine mesylate, which is in a nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV (Weinfurt et al.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
Patients whose background treatment regimen included a protease inhibitor or delavirdine received the lower dose.
This category includes nevirapine, efavirnz, and delavirdine.
34) There are three FDA approved NNRTIs: nevirapine, delavirdine, and efavirenz.
Delavirdine, Efaverenz, and Nevirapine are commonly used from this very specific drug class.
Currently, three groups of drugs are available for the treatment of the HIV infection: the nucleoside inhibitors of reverse transcriptase (zidovudine, didanosine, lamivudine, stavudine, abacavir, zalcitabine), the non-nucleoside inhibitors of reverse transcriptase (nevirapine, delavirdine, efavirenz), and the protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir, amprenavir, lopinavir).
Delavirdine mesylate inhibits cytochrome P-450, leading to a significant increase in methadone concentrations--the half-life is extended by almost 50%.
The K103N mutation causes high-level resistance to nevirapine as well as cross-resistance to other nonnucleoside reverse transcriptase inhibitors, including efavirenz and delavirdine, he said at a conference on retroviruses and opportunistic infections.
En la Grafica 2a y b se presentan las principales mutaciones que cambian codones de la secuencia de aminoacidos de la RT salvaje y que exhiben resistencia a los NRTI (zidovudine, didanosine, zalcitibine, stavudine, lamivudine, y abacavir) y a los NNRTI (nevirapine, delavirdine y enfavirenz).
Researchers in Denmark report that the protease inhibitor amprenavir (Agenerase) lowers the levels of delavirdine (Rescriptor).
The relative retention factors (k' values) for several other drugs that are commonly used as either antiviral drugs (DMP 266, delavirdine, and nucleosides) or drugs that are used to prevent or treat opportunistic infections (azole antifungals, macrolides, atovaquone, rifabutin, rifampin, trimethoprim, and sulfamethoxazole) are listed in Table 5.
Delavirdine mesylate (DLV, Rescriptor), Pharmacia & Upjohn