delavirdine


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Related to delavirdine: nelfinavir, enfuvirtide, Fosamprenavir, Amprenavir, Tipranavir, etravirine
  • noun

Synonyms for delavirdine

a non-nucleoside reverse transcriptase inhibitor (trade name Rescriptor) used to treat AIDS and HIV

References in periodicals archive ?
Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles.
Researchers in Denmark report that the protease inhibitor amprenavir (Agenerase) lowers the levels of delavirdine (Rescriptor).
The relative retention factors (k' values) for several other drugs that are commonly used as either antiviral drugs (DMP 266, delavirdine, and nucleosides) or drugs that are used to prevent or treat opportunistic infections (azole antifungals, macrolides, atovaquone, rifabutin, rifampin, trimethoprim, and sulfamethoxazole) are listed in Table 5.
Delavirdine mesylate (DLV, Rescriptor), Pharmacia & Upjohn
The citric juice appears to enhance the effects of the new drug, known as delavirdine, reported researchers at the University of Buffalo School of Pharmacy in Buffalo, N.
In two trials of delavirdine taken with other inhibitors of reverse transcriptase, investigators have found that they can accurately figure the odds that a patient will maintain good health.
US FDA PREGNANCY CATEGORIES FOR CURRENTLY APPROVED ANTIRETROVIRALS Drug FDA category Abacavir C Didanosine B Emtricitabine B Lamivudine C Stavudine C Tenofovir B Zalcitabine C Zidovudine C Delavirdine C Efavi renz D Nevirapine C Amprenavir C Atazanavir B Darunavir B Fosamprenavir C Indinavir C Lopinavir + C ritonavir Nelfinavir B Ritonavir B Saquinavir B Tipranavir C Enfuvirtide B FDA categories defined as: A: Adequate and well-controlled studies of pregnant women fail to demonstrate a risk to the fetus during the first trimester of pregnancy (and no evidence exists of risk during later trimesters).
Drugs: delavirdine and nelfinavir (see Table I) Peripheral consumption * Idiopathic thrombocytopenic purpura * Diffuse intravascular coagulopathy * Thrombotic thrombocytopenic purpura Peripheral sequestration/hypersplenism * Infections * Haemophagocytosis * Cirrhosis
The FDA approves the NNRTI delavirdine (Rescriptor).
Delavirdine mesylate inhibits cytochrome P-450, leading to a significant increase in methadone concentrations--the half-life is extended by almost 50%.
This is a very active antiretroviral of the NNRTI class (non-nucleoside reverse transcriptase inhibitor -- the same class as efavirenz, nevirapine, and delavirdine, the three NNRTI drugs currently approved in the U.
Delavirdine (Rescriptor), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Fortovase), and efavirenz (Sustiva) may increase ergot levels resulting in ergotism (nausea, vomiting, and vasospastic ischemia).
NNRTIs include delavirdine (Rescriptor), nevirapine (Viramune), and efavirenz (Sustiva).
Antiretroviral (ARV) drugs include protease inhibitors (PIs) such as ritonavir, indinavir, saquinavir, and nelfinavir; non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as nevirapine, delavirdine, and lovirdine; and nucleoside reverse transcriptor inhibitors (NRTIs) such as zidovudine (AZT), ddI, ddC, D4T, 3TC, and adefovir.
Serum samples for delavirdine, nevirapine, indinavir, nelfinavir, ritonavir, saquinavir, and zidovudine quantification were prepared for HPLC quantification by organic extraction.