As earlier published, intravenous treatment of refractory or relapsed AML patients with dactinomycin
The drug formulation includes dactinomycin
, a well-understood cancer drug, incorporated into a proprietary ANA-conjugated nanoemulsion.
Rhabdomyosarcoma is treated by a combination of surgery, chemotherapy, and radiation, with the most frequently used chemotherapy agents being vincristine, cyclophosphamide, dactinomycin
, adriamycin, ifosfamide, and virion protein VP-16 (etoposid).
We found that known aneugenic agents (bortezomib, dactinomycin
, methotrexate, nocodazole, triethylenemelamine, topotecan, vinblastine sulfate, and vincristine) were statistically significant inducers of [GFP.
doxorubicin (Adriamycin), bleomycin, mitomycin C and dactinomycin
VAB VI regimen: vinblastine, dactinomycin
(Cosmegen[R]), bleomycin, cyclophosphamide (Cytoxan[R]), and cisplatin
Chemical name Trademarker Class Source Actinomycin-D Dactinomycin
Non-alkaloid Streptomyces spp.
Bigmar intends to formulate and market a number of generic oncology drugs in IV bags, including, Fluorouracil, Doxorubicin, Methotrexate, Dacarbazine, Carboplatin, Aclarubicin, Ganciclovir, Azathioprine, Cyclophosphamide, Ifosfamide, Melphalan, Vincristinsulphate, Cisplatin, Amsakrine, Etoposide, Vinblastin and Dactinomycin