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Related to dacarbazine: doxorubicin, bleomycin, Temozolomide
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Synonyms for DTIC

the agency in the Department of Defense that provides scientific and technical information to federal agencies and their contractors

References in periodicals archive ?
In this phase 3 clinical trial, when Genasense was combined with dacarbazine, the most frequent serious adverse event occurring in more than 5 percent of patients was fever (5.
Genasense plus dacarbazine yielded superior results in a large randomized trial," said Dr.
Doxorubicin and dacarbazine chemotherapy was started after a left above-knee amputation.
reported that Zelboraf and Yervoy have replaced older agents in the first-line advanced melanoma setting compared to major European markets where respondents are still more likely to utilize Merck's Temodar/Temodal and generic dacarbazine in this patient population.
July 22, 2015 /PRNewswire/ -- AstraZeneca today announced that the Phase 3 SUMIT study of selumetinib in combination with dacarbazine for the treatment of patients with metastatic uveal melanoma did not meet its primary endpoint of progression free survival.
It has been compared to dacarbazine (DTIC), standard melanoma therapy, in a clinical trial with longer follow-up than the ipilimumab trial.
The standard treatment of advanced melanoma has for many years been single-agent dacarbazine (DTIC).
Genasense, the company's lead compound, has received "Fast Track" designation from the Food and Drug Administration, and the combination of Genasense plus dacarbazine is currently undergoing a Phase 3 trial in patients with advanced melanoma.
Array anticipates top-line results for the Phase 2 trial with selumetinib in combination with dacarbazine versus dacarbazine alone as first-line treatment in patients with BRAF-mutant melanoma to be reported in 2012.
Participants were randomly assigned to receive either Yondelis (345 patients) or dacarbazine (173 patients), another chemotherapy drug.
compared to dacarbazine in patients with advanced liposarcoma (LPS) or leiomyosarcoma (LMS) previously treated with an anthracycline and at least one additional chemotherapy regimen.
Study 309 is a randomised, open-label multicentre Phase III study comparing the efficacy and safety of eribulin in 452 patients (aged 18 or over) to dacarbazine.
The standard therapy arm consisted of four cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy followed by radiation therapy at 30 Gy limited to the involved field.
AstraZeneca is also completing a Phase 2 trial with selumetinib in combination with dacarbazine compared with dacarbazine alone as first-line treatment of patients with melanoma whose tumors harbor BRAF mutations.