Th researchers say the CNTs' topography boosts interactions between cells and long-term cultures, offering a fast and effective stimulation of the cytotoxic T cells
that are key to eradicate cancer.
Specifically, the investigators examined the NK cell cytoskeleton (the part of each cell primarily responsible for the spatial organization of its components) during target cell killing in comparison to that of cytotoxic T cells
These single-minded killers, white blood cells called cytotoxic T cells
, normally destroy only cells infected by viruses.
IL-21 is a novel cytokine with potent effects on a number of immune effector cells such as cytotoxic T cells
and natural killer cells.
Failure of infiltrating precursor cytotoxic T cells
to acquire direct cytotoxic function in immunologically privileged sites.