Among these, butyl p-tolyl sulfide, 6-methyl-4-chromanone and butylated hydroxyanisole appear to be the most interesting and exhibit an antiproliferative effect comparable to that of other antitumor compounds, including cisplatin, chromomycin, cytosine arabinoside and 5-fluorouracil.
The poster (Abstract #7051) entitled "A double blind placebo-controlled randomized phase III study of high-dose continuous infusion cytosine arabinoside (araC) with or without VNP40101M in patients with first relapse of AML" will be presented at McCormick Place, South Hall A1, Board 38E from 8:00 a.
Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and Daunorubicin.
The FDA approval followed a priority review and was based on 12-month data from a large head-to-head study comparing Gleevec with a combination of interferon-alpha and cytosine arabinoside (IFN/Ara-C), a traditional treatment for CML.
After immunohistochemical examination the patient was diagnosed with AML MO, and classic 7+3 induction chemotherapy regimen involving cytosine arabinoside and idarubicin combination protocol was initiated.
20 /PRNewswire/ -- Xanthus Life Sciences today announced the commencement of a Phase 2 study of Xanafide(TM) (amonafide malate) in combination with cytosine arabinoside (ara-C) for the treatment of patients with secondary acute myeloid leukemia (AML).