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  • noun

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pathological breakdown of cells by the destruction of their outer membrane

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These findings indicate the cytolytic efficacy of intraperitoneal lavage with sterile water for 10 minutes to some extent.
The cytotoxic function of NK-cells and CTLs is mediated by release of cytolytic granules, which contain perforin, granzymes, and other serine-specific proteases, into the immunological synapse that forms between the effector and the target cell.
C8[alpha] also contributes to the cytolytic activity of the MAC by interacting directly with membrane lipid.
A second aliquot of the nasal sample from animal D was inoculated onto trypsin-treated MDCK cells (3), and the propagated cytolytic virus was forwarded to St.
Although these data are not definitive, as a result, the use of rituximab--a CD20-directed cytolytic antibody--may be increasing among patients with RA and pulmonary disease, Dr.
Failure to regulate C3 and C5 convertases allows cytolytic membrane attack complex (MAC) to be generated on the surface of cells (6).
Most [alpha]-motor neurons were positive for perforin, the cytolytic protein used by CD8 T cells and natural killer cells to cause cell death (Figure, F).
on the morphology, levels of intracellular lysosomal enzymes, nonspecific esterase, cytolytic activity, etc.
In order to treat or prevent episodes of mild or acute rejection, the following treatment options may be considered: increased immunosuppression such as methylprednisolone (to suppress the inflammatory response), drugs like tacrolimus, mycophenolate mofetil (MMF), and cytolytic and clarithromycin therapy.
Additionally there was an increase in the cytolytic activity of CD8+ T cells.
In addition to its cytolytic domain, the pneumolysin molecule also has a complement-activating domain that can activate complement directly in the absence of anti-pneumolysin antibody.
7] by platelet granule--and/or cytolytic parenchymal cell-derived adenine nucleotides leads to nonselective cation permeability or dilatation to a size restriction of -900 Da, a phenomenon referred to as pore activity (4-6).
These claims cover fusion proteins comprising a heat shock protein, or portions thereof, and a human papillomavirus (HPV) protein antigen, or portion thereof, and being capable of inducing or enhancing a cell-mediated, cytolytic immune response in patients.
Bacterial two-component and hetero-heptameric pore-forming cytolytic toxins: structures, pore-forming mechanism, and organization of the genes.
He gave a long list of possible diagnoses that included atrophic vaginitis, a foreign body, allergic hypersensitivity and contact dermatitis, trauma, desquamative inflammatory vaginitis, erosive lichen planus, lactobacilli vaginosis, cytolytic vaginosis, streptococcal group A infection, ulcerative vaginitis with Staphylococcus aureus, and idiopathic ulceration associated with human immunodeficiency virus.