cyclooxygenase


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  • noun

Synonyms for cyclooxygenase

either of two related enzymes that control the production of prostaglandins and are blocked by aspirin

References in periodicals archive ?
Cyclooxygenase 2 inhibition in colorectal cancer therapy.
Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production.
Chan, A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors, Journal of Inflammation Research, 45(2), 68-74 (1996).
Systemic biosynthesis of prostacyclin by cyclooxygenase (cOX)-2: the human pharmacology of a selective inhibitor of cOX-2.
More pronounced inhibition of cyclooxygenase 2, increase in blood pressure, and reduction of heart rate by treatment with diclofenac compared with celecoxib and rofecoxib.
The different physiologic outcomes of inhibiting cyclo-oxygenase and the differences in prostaglandin action are due to the existence of two isoenzymes of cyclooxygenase, COX-1 and COX-2.
Sixty-two patients (42 men and 20 women; median age, 61 years), undergoing partial (10 cases) or radical (55 cases) nephrectomy for RCC were retrospectively analyzed by immunohistochemical analysis for CD44, cyclooxygenase 2, and PDGFR-[alpha] expression.
A systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.
Celecoxib, a cyclooxygenase (COX)-2 inhibitor, was administered for pain management and for potential antineoplastic activity.
The patients' blood samples revealed a direct inhibitory effect on cyclooxygenase (COX) activity.
After reviewing the results further, the cherries were found to be ten times as potent as aspirin for inhibition of cyclooxygenase 1 and 2 (COX-1 and COX-2) enzymes, which cause inflammation.
ibuprofen found in Advil[R] and Motrin[R], are cyclooxygenase (COX)-1 and COX-2 inhibitors.