Also found in: Dictionary, Medical, Acronyms, Encyclopedia, Wikipedia.
  • noun

Synonyms for cyclooxygenase

either of two related enzymes that control the production of prostaglandins and are blocked by aspirin

References in periodicals archive ?
Cyclooxygenase active bioflavonoids from Balaton[TM] tart cherry and their structure activity relationships.
COX-II, the cyclooxygenase isozyme inducible in response to inflammation (Lipisky, 1999), is believed to possibly inhibit inflammation without the adverse side-effects noted for COX-I inhibitors (Pairet et al.
The effect of an ethanolic extract of propolis, with and without CAPE, and some of its components on cyclooxygenase (COX-1 and COX-2) activity in J774 macrophages has been investigated.
Pure compounds 1-7 were assessed for their cyclooxygenase inhibitory activity at 37 [degrees]C by monitoring the initial rate of [O.
A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal cells.
Keywords: Rheedia gardneriana; Benzophenone; Endothelium; Nitric oxide; Lipoxygenase; Cyclooxygenase
Researchers have speculated that acetaminophen's lack of inhibition of cyclooxygenase, the key enzyme involved in the inflammatory response of asthma, may be one explanation for the potential link between acetaminophen use and asthma.
The mechanism underlying the aspirinibuprofen interaction may be due to "competitive inhibition of the acetylation site of cyclooxygenase in the platelet," according to the FDA statement.
Based on previous observations that tart cherry anthocyanins and their respective aglycone, cyanidin, can inhibit cyclooxygenase enzymes, we conducted experiments to test the potential of anthocyanins to inhibit intestinal tumor development in Apc(Min) mice and growth of human colon cancer cell lines.
Over the medium term companies will likely increase efforts placed on developing alternative approaches to regulating the cyclooxygenase pathway.
The licensed compounds are believed to selectively inhibit the activity of type-II cyclooxygenase (COX-2), an enzyme involved in the activity of substances that mediate inflammation, pain and fever.
AX feeding (200 ppm in diet) also lowered the protein expression of NF-[kappa]B, and the mRNA expression of inflammatory cytokines, including IL-1[beta], IL-6, and cyclooxygenase (COX)-2.
If the THF-diols or LTX-diols modulate luteinizing-hormone-releasing hormone release via pathways related to NO synthase, phospholipase A (PLA), cyclooxygenase (COX), or lipoxygenase (LOX), the compounds may directly or indirectly control breast or prostate cancer growth and proliferation via modulation of gonadotropin release and/or ovarian or testicular steroidogenesis.
GLT also down-regulated LPS-dependent expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2) in RAW264.