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  • noun

Synonyms for guanosine

a nucleoside component of DNA

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To make this discovery, Pfeifer and colleagues used mice to show that cyclic GMP reduced the secretion of pro-inflammatory hormones, which, in turn, shifted the "color code" of fat from white to brown.
In the present study, we found that the second messenger cyclic GMP may also be involved in the increase in midgut E-20-M activity (enzyme activity measured by radioassay).
By blocking PDE5, Viagra ensures that more cyclic GMP remains available to stimulate a sexual response.
and cyclic GMP and protects against oxidative stress elicited by proinflammatory agonists.
BNP stimulates cyclic GMP, which is not only a vasodilator but an inhibitor of the progressive heart muscle structural remodeling that leads to progression of heart failure," according to Jay N.
Depending on the direction of nitric oxide release and the site of cyclic GMP activation, differing biological effects can be observed.
A small molecule called cyclic GMP has now been recognized by scientists as the crucial messenger chemical in both types of cells that sense light in animals' eyes.
Phosphodiesterases (PDEs) are a family of enzymes that metabolize the intracellular messengers cyclic AMP (cAMP) and cyclic GMP.
SAANDS inhibit a novel form of cyclic GMP phosphodiesterase and selectively induce apoptosis (programmed cell death) in abnormally growing precancerous and cancerous cells.
Along with his mentor, he demonstrated that nitric oxide and cyclic GMP inhibit smooth muscle and mesangial cell growth and proliferation induced by serum and various growth factors, such as platelet-derived growth factor, epidermal growth factor, insulin-like growth factor, and fibroblast growth factor.
The company also reported laboratory findings that the cyclic GMP phosphodiesterase targeted by Aptosyn(TM) and other selective apoptotic antineoplastic drugs (SAANDs) is over-expressed in colonic neoplasias relative to normal colonic mucosal tissue.
Phosphodiesterases are a family of enzymes that metabolize the intracellular second messengers cyclic AMP (cAMP) and cyclic GMP.
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