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4 [micro]g croton oil and appropriate amounts of test samples were applied to the inner surface of the right ear of each mouse.
Croton oil, hydrocortisone and indomethacin were obtained from Sigma-Aldrich (Milan, Italy).
2]) by application of 80 [micro]g of Croton oil dissolved in an appropriate vehicle, as reported below.
Croton oil, indomethacin and ursolic and oleanolic acids were Sigma products (Sigma, Milan, Italy).
In mice ear edema (induced by phorbol-12-mirystate-13-acetate, croton oil and arachidonic acid), taraxasteryl acetate showed a topical anti-inflammatory activity similar to the extract, but at 1/20 of the dose.
Key words: Bauhinia tarapotensis, anti-inflammatory activity, triterpenes, croton oil ear test