= [[140 - age(yr)]*weight(kg)]/[72*serum Cr(mg/dL)] (multiply by 0.
Unlike in renal disease, where creatinine clearance
estimates provide a reasonable guide to alterations in drug dosage requirements, indicators of hepatic disease, such as elevated liver enzymes, low serum albumin concentrations and clotting abnormalities, cannot be directly related to drug clearance.
Your doctor will measure your creatinine clearance
by comparing the amount of creatinine in your urine to the amount of creatinine in your blood.
Many of the equations that use serum creatinine and weight to estimate the creatinine clearance
as a proxy for the level of kidney function were developed using young male populations; few were developed using older free-living individuals.
5) Creatinine clearance
measured using Cockcroft-Gault formula.
It also had relied on estimated creatinine clearance
calculated through the Cockcroft-Gault formula which is an imprecise measure of kidney function.
Conclusions: The 99mTc-DTPA clearance correlates significantly with 24-hour creatinine clearance
as well as with disease duration and can provide a simple and convenient index of kidney function in patients of early diabetic nephropathy.
Cockcroft DW, Gault MH: Prediction of Creatinine clearance
from Serum Creatinine.
Check serum creatinine and calculate creatinine clearance
3 months after initiation, then every 6 months while on PrEP medication.
It was observed that the patient weight was strongly correlated with distribution volume, while creatinine clearance
and the diagnosis of acute mieloblastic leukemia influence vancomycin clearance.
The GFRs, based on creatinine clearance
measurements, were assessed preoperatively and 3, 6 and 12 months postoperatively (GFR = [24-hour urine creatinine concentration x 24-hour urine volume]/[serum creatinine x 1440 min/day]).
Reduced renal function can also be assessed with creatinine-based formulae such as the Cockcroft-Gault formula (5), which calculates creatinine clearance
rate in mL/min, or the Modification of Diet in Renal Disease (MDRD)  formula, which calculates glomerular filtration rate in mL/min/1.
These blood samples were also used (for creatinine concentration) in the calculations of creatinine clearance
from the timed urine collections.
Renal function can be estimated using an estimated creatinine clearance
or by glomerular filtration rate, in addition to the 24-hour urine.
The measure of creatinine cleared during a 24-hour period defines the creatinine clearance
and correlates directly to the level of kidney function.