Restraint stress increases corticotropin-releasing hormone
mRNA content in the amygdala and paraventricular nucleus.
Appetite-suppressing effects of urotensin I and corticotropin-releasing hormone
in goldfish (Carassius auratus).
In the tightly regulated feedback loop of the HPA axis, the hypothalamus produces corticotropin-releasing hormone
(CRH) that stimulates the pituitary gland to release adrenocorticotropin hormone (ACTH), which stimulates the adrenal gland to release cortisol.
The hypothalamic "releasing" hormones, including corticotropin-releasing hormone
, growth hormone-releasing hormone, and prolactin-releasing hormone, stimulate the anterior pituitary, which then releases adrenocorticotropic hormone (ACTH).
Initial success in a small proof-of-concept trial with one corticotropin-releasing hormone
(CRH) antagonist came to naught when an association with elevated liver enzymes killed development.
2) Animal studies show a link between the hypothalamic-pituitary-adrenal axis and the hypothalamic-pituitary-ovarian axis in that acute corticotropin-releasing hormone
administration to ovariectomized monkeys inhibits gonadotropin-releasing hormone and luteinizing hormone.
People who suffered from childhood abuse and family stress have a tendency to release more corticotropin-releasing hormone
than individuals who have not experienced such stress.
Environmental stress as a developmental cue: corticotropin-releasing hormone
is a proximate mediator of adaptive phenotypic plasticity in amphibian metamorphosis.
The hypothalamus (as well as other regions of the brain) secretes a hormone known as CRH, for corticotropin-releasing hormone
Glucocorticoid hormones, which are often used to treat inflammatory illnesses like rheumatoid arthritis, asthma, or ulcerative colitis, block the release of both corticotropin-releasing hormone
(CRH) and ACTH.
2007) demonstrated that central insulin was as an appetite-suppressive peptide in chicken central nervous system, and this anorexigenic action was mediated by POMC and corticotropin-releasing hormone
One such effect is to stimulate the skin to synthesize corticotropin-releasing hormone
, a hypothalamic hormone that has immunomodulatory activity.
1) Downregulation of corticotropin-releasing hormone
(CRH) receptors in the pituitary glands and increased CRH levels have been documented in PTSD patients.
A hypothalamic hormone, corticotropin-releasing hormone
, controls the release of corticotropin from the anterior pituitary gland.
In addition, blood samples from each participant were analyzed to assess levels of placental corticotropin-releasing hormone
(pCRH), a stress hormone released from the placenta.