5) documented 18 published reports, with a total of 34 patients, of angina pectoris associated with coronary spasm
due to thyrotoxicosis, that have been confirmed angiographically since 1979.
A missense GIu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm
in the Japanese.
pentaphyllum leaves and of the pure gypenosides (Gy) on the pitressin--induced electrocardiographic and pressor alterations in the anaesthetized guinea-pigs % animals with ST (max height, mm) Treatment Dose (mg/kg) coronary spasm
(means [+ or -] s.
Nobody really understands what causes coronary spasm
Guidelines recommend not to use beta-adrenergic receptor blockers for patients with an AMI caused by cocaine, because of risk of exacerbating coronary spasm
The hypothesis that the infarction might have been caused by coronary spasm
followed by thrombosis may be supported by a similar case of a 28-year-old man who developed a myocardial infarct after abusing synephrine tablets.
Nitrates have not been demonstrated to improve mortality or recurrent myocardial infarction (17); however, they have many mechanisms (reduction in afterload, improvement in the coronary collateral circulation, relief of coronary spasm
, etc) through which they can improve symptoms.
786] [right arrow] C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
While the triggers of the events seem to be a variety of stresses, it is becoming clearer that the final common pathophysiology pathway may be coronary spasm
, although the details remain to be worked out (6).
The infarction probably resulted from coronary spasm
, platelet activation and in situ thrombosis triggered by the chronic consumption of a 'nutritional supplement' which contains synephrine, octopamine, tyramine and caffeine.
298] [right arrow] Asp) has been linked by several groups to the risk for coronary spasm
, coronary artery disease (CAD), and acute myocardial infarction (5-8).
These two events showed that the main mechanism is coronary spasm
with or without coronary lesions.
Administration of ergonovine maleate precipitated chest discomfort accompanied by diffuse right coronary spasm
exceeding 40% diameter reduction.
14) identified a NOS3 gene polymorphism in the 5' flanking region (T786C) that was significantly associated with coronary spasm
The correct and early diagnosis of coronary spasm
related acute coronary syndrome may prevent fatal complications.