Therefore, any reduction in aortic pressure not only increases coronary perfusion
pressure but also increases metabolic needs of coronary blood flow.
4) in Langendorff perfusion system (ADInstruments, Australia) at a constant coronary perfusion
pressure of 65 [+ or -] 1 mm Hg at 37 [degrees]C for 20-30 min (stabilization), then perfused at 20 [+ or -] 1 mm Hg for 40 min to produce a global low flow ischemia, and finally reperfused at 65 [+ or -] 1 mm Hg for 10 min.
pressure was measured by attaching the side arm of the aortic cannula to a pressure transducer (Isotec, Hugo Sachs Electronic, March-Hugstetten, Germany).
Substantial interruptions of chest compressions have detrimental effects on the success of cardiopulmonary resuscitation (14-16), reducing the likelihood of success of defibrillation due to immediate declines of coronary perfusion
He continued, "This demonstrated that the increase in coronary perfusion
, along with the already published scientific data demonstrating the positive hemodynamic and neurohormonal effects of EECP therapy, makes a very strong argument for the use of enhanced external counterpulsation therapy in treating stable angina and compensated heart failure patients.
The role of heart rate in myocardial ischemia from restricted coronary perfusion
However, those studies involved follow-up of only 6-24 months' duration--not long enough for the early hazards of percutaneous intervention or coronary artery bypass surgery to be outweighed by the longer-term benefits of the resultant improved coronary perfusion
8 million coronary perfusion
imaging studies performed annually.
This is important because the historical concern has been that some hemoglobin-based oxygen carriers have caused coronary vasoconstriction that would reduce coronary perfusion
and result in myocardial ischemia.
The rate doesn't provide adequate coronary perfusion