symptom

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  • noun

Synonyms for symptom

Synonyms for symptom

something visible or evident that gives grounds for believing in the existence or presence of something else

Words related to symptom

(medicine) any sensation or change in bodily function that is experienced by a patient and is associated with a particular disease

Related Words

anything that accompanies X and is regarded as an indication of X's existence

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References in periodicals archive ?
Constitutional Symptoms Response The majority of patients reporting constitutional symptoms at baseline demonstrated a Complete Resolution or Marked Improvement of their symptoms, including night sweats, pruritus and bone pain.
The majority of subjects reporting constitutional symptoms at baseline experienced complete resolution or marked improvement by six months with measurable improvement within the first month of therapy.
She denied fevers, fatigue, and other constitutional symptoms, and she had no skin or scalp lesions.
Although rare, GI tract histoplasmosis should be in the differential diagnosis of patients from endemic areas on chronic hemodialysis who present with unexplained diarrhea and constitutional symptoms such as fever and weight loss.
Compared with controls, patients were more likely to report the following constitutional symptoms either continuously or repeatedly during the previous year: fevers, chills, sweats, and fatigue (Table 1).
INCB18424 provided rapid and sustained reduction in splenomegaly, alleviation of constitutional symptoms, improvement of performance status and exercise capacity and weight gain.
Pacritinib has been well tolerated and has shown activity in alleviating MF-associated splenomegaly and constitutional symptoms with lack of myelosuppression.
The following clinical data were also recorded: indications for surgery, known TB contacts, presenting symptoms (presence of nasal obstruction, nasal discharge, and sore throat), and constitutional symptoms (weight loss/poor weight gain or fevers).
No history of chronic headache or constitutional symptoms of fever, nausea, or vomiting were described by the patient.
Incyte's Executive Vice President, Chief Drug Development and Medical Officer, added, "The updated data from the Phase II trial in myelofibrosis, our most advanced program for INCB18424, demonstrate that the dosing regimens that are being used in our Phase III trials, COMFORT-I and COMFORT-II, have the potential to be well tolerated and provide durable clinical improvement in both splenomegaly and the debilitating constitutional symptoms seen in the majority of MF patients.
The possible mechanism of constitutional symptoms and leukocytosis includes aberrant cytokine production.
3) Cervical tuberculosis is usually associated with constitutional symptoms such as fever, weight loss, and night sweats.
Table 1 Important causes of back pain Cause Risk factor/clinical features Fracture History of trauma Tumor Age > 50 or <20 yr, history of cancer, pain worse in supine position or at night, constitutional symptoms Infections Immunosuppression, recent bacterial infection, IV drug abuse, constitutional symptoms Cauda equina syndrome Acure urinary retention, saddle anesthesia, lower-extremity weakness, reduction in anal sphincter tone Spinal stenosis Pseudoclaudication with pain that increases with walking and standing and is relieved by sitting or leaning forward Radiculopathy Sensory loss, weakness, and radiating radicular pain
Incyte Corporation (NASDAQ: INCY) announced today that it has entered into a collaboration and license agreement with Novartis for two of its investigational hematology-oncology therapies: INCB18424, an oral JAK1/JAK2 inhibitor that is in Phase III development for myelofibrosis, a serious life-threatening neoplastic condition characterized by varying degrees of bone marrow failure, splenic enlargement and debilitating constitutional symptoms, and INCB28060, an oral cMET inhibitor that is about to enter Phase I development as a potential treatment for multiple cancers.
SB1518 showed promising efficacy in alleviating MF-associated splenomegaly and constitutional symptoms at a dose that induces minimal myelosuppression.
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