Given the ubiquitousness of conjugative
plasmids within multidrug-resistant bacterial strains, it can conceivably shift the equilibrium towards success in a variety of refractory clinical infections.
While the world is bracing for an epidemic of infectious diseases bearing plasmid-mediated Colistin resistance (15), a vast and ubiquitous reservoir for conjugative
transmissible resistance to fosfomycin exists and can preclude its efficacy against extremely drug-resistant bacteria if the guidelines for the indiscriminate use of fosfomycin-trometamol are not urgently revised to safeguard this potent and well-tolerated agent.
transfer of these large plasmids thus plays an important role in the evolution of bacteria species .
Pheromone responses and high-level aminoglycoside resistance of conjugative
plasmids of Enterococcusfaecalis from Greece," Journal of Antimicrobial Chemotherapy, 2000; 46(6); 1013-1016.
56 ppm was assigned to the carbonyl carbon, C(3), which appeared downfield due to the conjugative
effect of N(2)-N(3) core in the hydrazone.
The increasing resistance in enterobacteria could be attributed to the presence of conjugative
plasmids carrying resistance genes in the environment (LIEBANA et al.
The electrophile is subjected to reductive or conjugative
modification by phase II enzymes (glutathione-S-transferases (GSTs), UDP-glucuronosyltransferases (UGTs), catechol-O-methyl transferases (COMT), N-acetyl transferases (NATs), and many others).
Pathogens of bovine respiratory disease in North American feedlots conferring multidrug resistance via integrative conjugative
Co-carriage of PMQR determinants along with ESBL-encoding genes on conjugative
plasmids have also been reported by a number of investigators.
coli S17 strains were transformed by electroporation for insertion of the conjugative
vector fused to the promoter of interest, as established by Sambrook and Russel (2001), followed by cellular growth of the bacterial isolates onto Luria-Bertani (LB) agar and 12.
trimethoprim or trimethoprim and kanamycin resistance plasmids with lengths of 80 to 110 kb were present.
The spectra clearly demonstrate that rutin undergoes bathochromic shifts in the presence of metals due to increased conjugative
effect (Table 2).
On the one hand, these C=C double bonds and C=O bonds from AAEM fragments formed conjugative
effects, leading to the reduction of wavenumbers of C=C double bonds; on the other hand, the C=O bonds in peptides from proteins presented peaks near 1640 [cm.
plasmid DNA transfer in Helicobacter pylori mediated by chromosomally encoded relaxase and TraG-like proteins.
Of more concern is the fact that these Enterobacteriaceae are the most notorious organisms in nature known to contribute significantly to the spread of antibiotic resistance in the community through conjugative