The WHO study reported that subjects for whom the method failed were significantly heavier than those for whom the method resulted in complete abortion
A complete abortion
was defined as complete expulsion of products of conception, while an incomplete abortion was the retention of fetal tissue in the uterus, resulting in the need for uterine evacuation; both were determined clinically.
Since 1996, more countries have experienced a decline in abortion rates than an increase, among those with complete abortion
counts and trend data.
of misoprostol two days after taking mifepristone unless a complete abortion
has already been confirmed before that time.
Among women who took misoprostol at home, the proportion who had a complete abortion
ranged from 86% (in India) to 97% (in Albania); the average success rate was 90%.
A previous study in a Latin American country where abortion was illegal documented a similar MA protocol involving two follow-up visits; providers seemed particularly eager to ensure that women had a complete abortion
as soon as possible, (19) likely because of the fear that women might seek care at a different clinic if they had prolonged bleeding or other unexpected symptoms.
ACOG endorsed the intravaginal use of 800 mcg misoprostol as part of the off-label regimen in a Practice Bulletin issued in October 2005, noting that it "decreases the time to expulsion, results in fewer side effects, and improves complete abortion
rates when compared with oral administration of a 400-mcg dose of misoprostol.
took an average of 18 hours for women in the vaginal misoprostol group, 21 hours for those who received intra-amniotic prostaglandin and 31 hours for those who took oral misoprostol.
2 The regimen requires multiple office visits, and the use of equipment such as ultrasound is common to date the pregnancy and confirm the complete abortion
of the baby.
We calculated the abortion rate (the number of abortions annually per 1,000 women aged 15-44) for each of the countries covered, as well as the proportion of all pregnancies that end in abortion for the countries with complete abortion
At 24 hours, the complete abortion
rate was higher in the vaginal group: 85.
The younger women had a complete abortion
rate of 90%, which was slightly higher than the 87% complete abortion
rate among those over age 21, but the difference was not significant.
The complete abortion
rates at two weeks was 93% and 90%, respectively, for the two groups.
Comparison of seven misoprostol regimens, using various doses and timings of oral or vaginal misoprostol, showed poor complete abortion
rates varying from 39% to 60% with five of the regimens.