Fibrinolytic agents such as tPA are also given to provide localized clot lysis
in the coronary vasculature in order to clear nascent thrombus in the coronary arteries.
administration administration stay 1 N/A 0.
Plasma TAFI levels influence the clot lysis
time in healthy individuals in the presence of an intact intrinsic pathway of coagulation.
Treatment not directed at prevention of thrombus extension, cbt formation, or clot lysis
is ineffective and carries higher risk.
Because a recent report shows that the proCPU concentration in human plasma is a major determinant of the clot lysis
time (26) and because no reference values for proCPU concentrations are known, we determined proCPU concentrations in a healthy population to establish a reference interval for this potential new marker of fibrinolytic capacity.
Of the 145 sequential films of the ultrasound catheters, 69/145 (48%) showed some clot lysis
had occurred since the previous 15 min film.
These can include increasing the risk of bleeding in the brain as well as remote areas such as the gums, gastrointestinal tract, retroperitoneum, or elsewhere, as well as direct interference with clot lysis
With the TEG, a whole-blood clot lysis
index [maximum amplitude/amplitude 60 ratio (MA/A60)] can be determined and may be useful in detecting hyperfibrinolysis.
Ohman J, Servo A, Heiskanen O: Effect of intrathecal fibrinolytic therapy on clot lysis
and vasospasm in patients with aneurysmal subarachnoid hemorrhage.
When blood flow to the offending thrombus was not restricted (unimpeded flow), locally delivered TPA and plasmin both induced virtually complete clot lysis
and restoration of blood flow to the ischemic limb compared with the absence of response with saline alone.
Two methods that have been used are euglobulin lysis time and whole-blood clot lysis
After defining the optimal therapeutic ultrasound parameters to be used for efficient clot lysis
First Small Molecule Inhibitors of PAI Are Shown to Enhance Clot Lysis