Laboratory diagnosis of clostridial myonecrosis is commonly based on a fluorescent antibody test (FAT) or isolation of the etiological agent.
The aim of this study was to apply a standardized immunochemistry test for the diagnosis of clostridial myonecrosis in 38 formalized tissue samples from ruminants with clinical and post mortem history of blackleg or gas gangrene.
has also been reported following intestinal surgery, black tar heroin injection (skin popping), and in association with obstetrical complications, such as retained placenta, prolonged rupture of membranes, and spontaneous abortion.
Hyperbaric oxygen is generally considered an important adjunct in the treatment of clostridial myonecrosis
or gas gangrene.
Approved indications for clinical HBO administration include; treatment of decompression sickness, carbon monoxide poisoning, clostridial myonecrosis
(gas gangrene), crush injuries, compartment syndrome, or other injuries resulting in acute traumatic ischemia.
The diagnosis of clostridial myonecrosis
is based on the clinical history, anatomical and pathological findings and identification of the etiological agent involved, which can be accomplished through bacterial isolation, direct immunofluorescence or IHC.