His focal seizures, evidenced by subtle automatisms, quickly developed into a bilateral, convulsive seizure involving both tonic and clonic
Patients with drug refractory epilepsy, include atonic, clonic
, myoclonic, absence, tonic clonic
seizures, after two years treatment with at least two anticonvulsive drugs (15,37,38,49,50,51);
Absence seizures are usually accompanied by subtle bilateral motor signs such as rapid blinking of the eyelids, chewing movements and clonic
movements of the hands.
There were no significant differences in latencies to the onset of myoclonic and clonic
seizures and the percentage of the animals showing tonic seizure and death between the water and olive oil groups.
In the literature, three patients who had recurrent seizures after oral ingestion of 41 mg/kg, 59 mg/kg and 68 mg/kg respectively and patients who had generalized tonic clonic
seizures after oral ingestion of 1-1,5 teaspoon (1 000-1 500 mg) have been reported (8).
3%) with generalized tonic clonic
accounting for 53 patients while partial seizures accounted for 23 patients (39.
Half a year after finishing the treatment, the patient presented a generalized tonic clonic
seizure and he came into our clinic for further investigations.
4 JME begins in the second decade of life with myoclonic jerks (MJ) and in most of patients generalized tonic clonic
seizures (GTCS) are found.
seizures- repetitive rhythmic jerking involving both sides of the body
Most of these children (11) had co-morbid epilepsy: generalized tonic clonic
seizures (5); myoclonic seizure (2); electrical status epilepticus of sleep (1); and atypical absence (1).
Films from the following four behaviors were recorded: starting time of clonic
seizures after injection of Primphos (second), Generation time of death after Primphos injection (second), mortality after injection of Primphos (persentage) and type of seizures induced by injection of Primphos (percentage).
Seizure Threshold is empherically defined as the minimal electrical dose that induces generalised tonic clonic
1A]ARs produced a significantly greater latency to myclonic jerk and tonic clonic
state compared to wild-type in flurothyl-induced seizures.
The onset of clonic
and tonic actions induced by PTZ in the control animals was found to be 47.
Other types of convulsive generalized seizures include clonic
seizures involving rhythmic jerking of extremities without a preceding tonic phase, and tonic seizures involving full body rigidity (Yamamoto et al.