Toxic effects of clomiphene citrate
range from mild (secondary side effects) to severe (genotoxic effects).
Early miscarriage and fetal malformations after induction of ovulation (by clomiphene citrate
and/or human menotropins), in vitro fertilization, and gamete intrafallopian transfer.
15) There are few clinical data on the effect of clomiphene citrate
on lipids, breast tissue, or the cardiovascular system.
Follicle-stimulating hormones usually are prescribed for patients who have not responded to clomiphene citrate
or failed to conceive following three ovulatory cycles of that therapy.
The relative success of gonadotropin-releasing hormone analogue, clomiphene citrate
, and gonadotropin in 1,009 cycles of in vitro fertilization.
She had been treated previously with clomiphene citrate
, a fertility drug that increases the incidence of multiple births among those who subsequently become pregnant from 1 percent to 8 percent.
Drugs used for ovarian stimulation: clomiphene citrate
, aromatase inhibitors, metformin, gonadotropins, gonadotropin-releasing hormone analogs, and recombinant gonadotropins.
50) Another trial showed that when women with hypothyroidism were given levothyroxine alone or with clomiphene citrate
and/ or dexamethasone, ovulation was normalized.
The study comparing Klimadynon (Cimififuga racemosa) with clomiphene citrate
remains the first-line treatment for PCOS-related anovulatory infertility (9).
Using clomiphene citrate
for ovarian stimulation led to a higher live birth rate, compared with using letrozole, and a lower multiple gestation rate, compared with using gonadotropins, in a randomized, multicenter trial that included 900 women.
7,8) Insulin sensitisation using drugs such as metformin, a biguanide, has been used as both an adjunct and an alternative to clomiphene citrate
in patients who are not successful in achieving ovulation or pregnancy.
The abstracts John Theurer Cancer Center will present focus on the following topics: laparoscopic adrenalectomy (horseshoe kidney), hypogonadal patients receiving clomiphene citrate
or anastrozole for infertility, robot-assisted radical prostatectomy and CT-fused indium-111 capromab pendetide immunoscintigraphy in management of recurrent prostate cancer.
Fertility Drugs: Drugs such as Clomiphene Citrate
(Clomid) are frequently prescribed to trigger egg growth and ovulation for women seeking to get pregnant.
If a woman is unable to lose weight or if modest weight loss does not restore ovulation, an ovulation-stimulating drug such as clomiphene citrate