These results lead us to conclude the parsnip does have bioactive principles that interfere with the cell division cycle (CDC) of the onion roots, resulting in its acceleration, and inhibition in different doses as evidenced by the mitotic indices and chromosomal mutations.
He said that because different forms of cancer are associated with different chromosomal mutations, they believe analysis of exosome DNA taken from blood samples may not only help determine the presence of a cancerous tumor somewhere in the body but also identify mutations without a need for tumor sample.
Efflux pumps act in response to bacterial stress and the expression of pumps reduces the accumulation of organic compounds or antimicrobial agents within the cell and can also be caused by chromosomal mutations, resulting in multiple antibiotic resistance (MAR).
To the Editor: In pneumococci, resistance to fluoroquinolones is associated with chromosomal mutations in the quinolone-resistance-determining regions (QRDR) of type II topoisomerase enzymes, predominantly gyrA and parC.
Molecular studies have revealed immense complexity in the structure of the eukaryote genome, and this structure may constrain the types of chromosomal mutations possible (King gives several examples [pp.