This method also accurately differentiated allelic variants from chromosomal DNA
templates, thus eliminating the need for pre-assay PCR amplification of the locus.
In Southern blots, a hybridization signal was only detectable in correspondence of the band of chromosomal DNA
was obtained by the procedure of Antonishyn et al.
The expressed sequence of ssDNA (oligo) was used to target specific chromosomal sites and attach itself to chromosomal DNA
, forming triplex structures, which can induce recombination and mediate directed genome modification and potentially gene repair.
Such advantages include reduced risk of an autoimmune response, allowing for repeat administrations of the gene medicine, and reduced risk of irreversible genetic alterations caused by integration of the administered DNA into the patient's own chromosomal DNA
The DNA pre-integration complex enters the nucleus, enabling the DNA to integrate into the target cell's chromosomal DNA
Pulsed-field gel electrophoresis (PFGE) of macrorestricted chromosomal DNA
was performed to establish the genetic relatedness of the VRE isolates (10).
After purification, the WGA product can be analyzed in a manner similar to any genomic or chromosomal DNA
Integrons carrying antimicrobial resistance genes have been found in plasmids and transposons (and transposon-like elements) and in the chromosomal DNA
of some bacteria.
The technique traces the amount of Y chromosomal DNA
in the maternal blood to determine gender.
Molecular typing of all isolates was performed by pulsed-field gel electrophoresis (PFGE) with Sma I-digested chromosomal DNA
aureus strains from the patient and the health-care worker were compared by pulsed-field gel electrophoresis (PFGE) using SmaI- and EagI-digested chromosomal DNA
These questions include how transcription factors and RNA polymerases have evolved to rapidly find and bind their specific binding sites on chromosomal DNA
, how the initiation of DNA replication is coordinated with cell growth, how cells can filter out leakage during replication of repressed genes, and other questions related to how the physical limitations of molecular interactions constrain cellular regulation.
Renowned British artist Adam Ball has used highly magnified photographs of his own blood cells and chromosomal DNA
as a starting point for his latest body of work, and first solo exhibition in Bahrain, called "Resolution".
Telomerase acts on chromosomes by protecting chromosomal DNA
through sustaining their protective telomeres.