References in periodicals archive ?
One of the main concerns of patients with Maffucci syndrome is the malignant transformation of the enchondromas into chondrosarcomas and the hemangiomas into vascular malignancies.
Chondrosarcomas have been found in the middle fossa (64% of reported cases), in the anterior fossa (14%), in the posterior fossa (7%), and in both the posterior and anterior fossae (14%).
Transformation into chondrosarcoma generally is indicated when cortical breakthrough is noted along with soft-tissue involvement.
SPARC is overexpressed in angiosarcoma, chondrosarcoma, EHE and osteosarcoma
For example, from clinical and radiologic interpretations of cartilaginous neoplasm such as enchondroma versus well-differentiated chondrosarcoma, the pathologist should extract a diagnosis that includes prognostic implications as well as possible further treatment and follow-up.
Although chondrosarcomas are considered the most common primary malignancy of the chest wall and sternum, it is nevertheless a rare lesion as reported in the literature.
Extraskeletal myxoid chondrosarcoma (EMC) is an uncommon low-grade sarcoma of the soft tissue, usually presenting as a slow-growing mass in men in their fifth to sixth decades.
Conventional intramedullary chondrosarcomas typically occur in the fourth or fifth decades, with a male to female predominance of 1.
Malignant change in a previously benign tumour is largely restricted to conditions such as multiple exostoses (diaphyseal aclasis) and multiple enchondromatosis or Ollier's disease, where a relatively slow-growing chondrosarcoma develops in middle age.
The limited papers written on Cranial Chondrosarcomas said that if it was low grade, the prognosis was 10 years plus, but if it was high grade then it was at best two years.
Chordomas and Chondrosarcomas of the Cranial Base, in Wilkins RH, Rengachary SS (eds).
Gay E, Sekhar LN, Wright DC: Chordomas and chondrosarcomas of the cranial base.
The Massachusetts group has also treated 67 patients with chordomas or chondrosarcomas of the base of the skull or cervical spine--a rather rare tumor, Austin-Seymour says.
8,9 Chondrosarcomas are largely resistant to chemotherapy and radiotherapy, and the standard therapeutic strategy is surgery.
A number of lesions and disease processes have been described within the petrous apex, including cholesterol granulomas, petrous apicitis, cerebrospinal fluid cysts, encephaloceles, epidermoids, effusions, mucoceles, carotid aneurysms, asymmetric pneumatization, chordomas, chondrosarcomas, metastases, paragangliomas (glomus tumors), meningiomas, and schwannomas, (1-8) Characteristic presenting symptoms, as well as findings on magnetic resonance imaging (MRI) and computed tomography (CT) scans, are essential for differentiation of the lesion.
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