choline

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Related to choline acetyltransferase: choline acetylase
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Words related to choline

a B-complex vitamin that is a constituent of lecithin

References in periodicals archive ?
Cloning of chicken choline acetyltransferase and its expression in early embryonic retina.
To answer these questions, we evaluated PC12 cells in the undifferentiated state (CPF without NGF), at the initiation of differentiation (inclusion of CPF simultaneously with the addition of NGF), and at mid-differentiation (CPF added after several days of NGF pretreatment), evaluating cell viability, DNA synthesis associated with cell replication, and enzymatic markers that characterize the cholinergic or catecholaminergic phenotype: choline acetyltransferase (CHAT) and tyrosine hydroxylase (TH), respectively.
Data regarding the effects of SERMs on cognitive function and central nervous system (CNS) disorders are scant, he added, However, SERMs appear to increase choline acetyltransferase (ChaT) activity which plays a role in the pathology of Alzheimer's disease.
Insulin controls the activities of glycolytic enzymes in nonneuronal tissues and enhances the activities of pyruvate dehydrogenase complex [45] and choline acetyltransferase [46] in nervous tissue.
Similar correlations were noted between enhanced choline acetyltransferase immunoreactivity and decreased calcineurin," Dr.
The most important changes observed are a decrease in the acetylcholine neurotransmitter, as well in levels of the respective enzymes that synthesize and degrade acetylcholine, choline acetyltransferase and acetylcholinesterase (AChE) (Perry et al.
The concentration of ACh exhibits distinct peaks during early cleavage divisions, but the major, sustained increases occur after the beginning of gastrulation, in tandem with transcription of zygotic genes and attendant rises in choline acetyltransferase, the enzyme that synthesizes ACh (Buznikov et al.
Postmortem studies have found a reduction in choline acetyltransferase activity in the cortex, hippocampus, and striatum, suggesting reduced nicotinic receptors in those regions.