Had we only dealt with phenomenal visual experiences after acquired blindness, the problem would not have been substantial; we know that, as a release phenomenon, "phantom vision" occurs rather frequently after either peripheral or central blindness
(Schultz & Melzack, 1991).
Symptomatic VMA is increasingly being recognized as an important sight-threatening condition that can lead to distorted vision, and even central blindness
However, a significant number of cases of the "dry" form of AMD can progress to the "wet" form, where blood vessels underneath the retina begin to grow, leading to central blindness
Symptomatic VMA including macular hole is a progressive condition that if left untreated generally leads to significant visual distortion, deterioration in vision, and in some cases central blindness
Novartis estimates that 250,000 to 300,000 patients in Europe suffer from visual distortion, decreased visual acuity and central blindness
A key finding from the TG-MV-006 study that was presented in Berlin related to patients who had been diagnosed with full thickness macular hole (FTMH), a severe condition which can lead to irreversible vision impairment, including central blindness
, if not treated by eye surgery (vitrectomy).