From a different perspective, of autopsies done on patients with sudden cardiac death, but without coronary arterial occlusion, granulomatous disease consistent with cardiac sarcoidosis was found in 10 of 184 hearts.
For instance, an argument against pure immune dysregulation or autoimmunity is that cardiac sarcoidosis is known to recur in recipients of heart transplants despite the allograft likely having different immunogenic antigens.
31,32) Recently, an interesting study was performed on a patient with isolated cardiac sarcoidosis.
There have been numerous clinical and pathologic studies published regarding cardiac sarcoidosis.
Most importantly for this subject, patients with proven cardiac sarcoidosis had significantly higher levels than noncardiac sarcoid patients or idiopathic DCM patients.
38) Grossly the granulomatous lesions of cardiac sarcoidosis can appear as yellow, white, tan, light brown, or grey irregular tumorlike infiltrates (36) (Figure 1).