capsid


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  • noun

Synonyms for capsid

the outer covering of protein surrounding the nucleic acid of a virus

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References in periodicals archive ?
Meruelo told SCIENCE NEWS he believes that hypericin inhibits HIV infection by stiffening the HIV capsid, possibly in a manner similar to the newly developed drugs that inhibit rhinoviruses.
The first agreement announced today is with the University of Louisville's James Graham Brown Cancer Center and grants ACT exclusive worldwide development and commercialization rights to monovalent vaccines derived from the minor capsid protein (L2) of human papillomavirus.
6 differed by [approximately equal to] 38% in VP1 sequences; most amino acid sequence variation occurred in the capsid protruding domain (29%; 163/556).
A detailed description of the complete HIV capsid will provide a roadmap for developing drugs that can disrupt its formation and thus prevent infection by HIV.
Bacilligen's other product candidates, which include vaccines for AIDS, cancer, and influenza, are based on a novel bacteriophage capsid system, BVS, for the delivery of nucleic acid therapies and vaccines for cancer and infectious disease.
4 variants Apeldoorn 2008 and New Orleans 2009 and has several amino acid changes on the main epitope in the capsid P2 domain (10).
They reasoned that B cells would almost never encounter a bacterial cell wall or viral capsid alone; an intact cell wall would almost always also contain other molecules that activate the innate immune response as well.
A total of 22 NoV capsid and 15 polymerase genotypes were detected among the genotyped samples.
In order to find out how DNA could easily escape through such a tiny opening in the capsid, Evilevitch did separate studies on Herpes Simplex virus type 1 (HSV-1), which infects humans, and bacteriophage lambda, which infects bacteria.
NVR-1221 is a small molecule, direct acting antiviral, for oral administration in patients with Chronic Hepatitis B (CHB) that inhibits the HBV core or capsid protein.
VDPV strains are defined as follows: 1) strains of types 1 and 3, which have <99% nt sequence identity to the capsid viral protein (VP) 1 coding region of the corresponding Sabin reference strain; and 2) VDPV strains of type 2, which have <99.
In contrast, viral capsid, the protein coat of the virus, induced inflammation similar to intact virus.
Bacilligen is a privately held biotechnology company focusing on the development of recombinant mycobacteria for cancer therapy, as well as a novel bacteriophage capsid system, BVS, for the delivery of nucleic acid therapies and vaccines for cancer and infectious disease.
NVR-1221 is a small molecule, direct-acting antiviral, for oral administration in patients with Chronic Hepatitis B (CHB) that inhibits the HBV core or capsid protein.
Two ORFs, located at the 5' end of the genome (ORF1a and ORF1b), encode nonstructural proteins, and ORF2, located at the 3' end, encodes the capsid protein (1).