Half of the subjects took 325 milligrams of buffered aspirin
every other day, while the remainder received a placebo.
5 mg for a suspected acute MI taken as soon as the infarct is suspected and then daily for at least 30 days; and a statement that this use of aspirin applies to both solid, oral dosage forms and buffered aspirin
Recommended Dosage: 20 mg, 40 mg, or 80 mg of Pravachol, with either 81 mg or 325 mg of buffered aspirin
For people with heart disease for whom treatment with both Pravachol and Buffered Aspirin
is appropriate, PRAVIGARD PAC along with diet can lower the chances of dying of heart disease, or having a heart attack or stroke.
If using aspirin for dogs, give buffered aspirin
tablets at a dose of one-half adult five-grain tablet for each 25 pounds of body weight once or twice a day.
PRAVIGARD PAC contains two widely used medications -- Pravachol(R) (pravastatin sodium) tablets and buffered aspirin tablets -- co-packaged with each daily dose side-by-side.
The recommended daily dose of PRAVIGARD PAC is 40 mg of Pravachol(R) (pravastatin sodium) with either 81 mg or 325 mg of buffered aspirin.
The provision of two more pravastatin doses swayed a Food and Drug Administration expert panel towards supporting approval of a copackaged product combining the lipid-lowering drug with buffered aspirin.
In January, the majority of the same panel had voted against approval, largely because there was only one available dose of pravastatin-40 mg-in combination with either 81 mg or 325 mg of buffered aspirin.
The potential for inadequate titration was among the concerns that led the majority of a Food and Drug Administration expert panel to recommend against a fixed-dose combination of the lipid-lowering drug pravastatin and buffered aspirin
People who experience stomach irritation should ask their doctor whether an enteric coated or buffered aspirin
product might help reduce the incidence of stomach related side effects.