To validate the relevance between TAZ expression and treatment response in NSIP, we also compared TAZ expression in fibroblasts, bronchiolar
cells, and alveolar cells between the good response and nonresponse groups.
Cellular response in naphthalene-induced Clara cell injury and bronchiolar
epithelial repair in mice.
very severe histopathological changes of alveolar oedema, haemorrhage, congestion and necrosis, and bronchiolar
1992) Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar
epithelial Clara cells.
Computed tomographic imaging of bronchiolar
Degenerative and necrotic changes were observed in bronchiolar
Viral antigen was detected in neurons in the brain, bronchiolar
epithelium and macrophages in the lungs, bile duct epithelium in the liver, and macrophages and lymphocytes in lymph nodes.
It has been called under various names such as intravascular bronchiolar
and alveolar pulmonary tumor.
Using a novel 3D culture model that mimics the environment of the lung, the researchers showed that even a single lung stem cell could be coaxed into producing alveolar and bronchiolar
CC10 with primary expression in the uterus and non-ciliated bronchiolar
cells has an anti- inflammatory effect on the urogenital and respiratory
Immunohistochemical staining of NOS isoforms, PAI-1, [alpha]-SMA, IL-4, IL-13, and bFGF-positive cells in alveolar septa, as well as endothelial, myofibroblast, and smooth muscle cells in terminal bronchiolar
arteries, were quantified by stereology at 400 x magnification with an eyepiece systematic point-sampling grid with 100 points and 50 lines used to count the fraction of lines overlying the positively stained structures (27).
Squamous metaplasia of bronchiolar
epithelium was seen in 49 (6%) of 810 cases.
1997) have found that Cd-exposed lungs showed acute and more chronic pulmonary inflammation in both rats and mice with bronchiolar
and alveolar lesions.
As an example of the benefits potentially associated with biomarkers for ILD, Krebs von den Lungen-6 (KL-6) is a high-molecular-weight glycoprotein antigen (classified as a MUC1 mucin), first described by Kohno et al in 1985, that in normal lungs is expressed mainly on type II pneumocytes and bronchiolar
epithelial cells, while only weakly in basal cells of the terminal bronchiolar
epithelium, a small number of middle layer cells of the bronchial epithelium, and serous cells of the bronchial gland.
From the pathophysiological point of view, respiratory failure occurs due to irreversible obstruction of the bronchiolar