2009) who reported increase in weed dry weight with increased competition periods in blackseed and fennel crops respectively.
Effect of weed competition periods on the growth and yield of blackseed (Nigella sativa L.
Effect of competition periods on growth and yield of blackseed (Nigella sativa L.
rugelii; American, purple-stemmed or blackseed
plantain; Entrance Road, gravel lot and adjacent fields, open woodlands; Abundant and widespread; C = 0; BSUH 17887.
In vitro and in vivo, blackseed preparations have also demonstrated significant antineoplastic activity (Salomi et al.
Effects of blackseed oil on release of t-PA antigen
1, treatment of HUVEC and HUA-EC with increasing concentrations of blackseed oil for 24 h resulted in a concentration-dependent increase of t-PA antigen in the CM of such treated cells.
2, PAI-1 antigen increased significantly in the CM in a concentration-dependent manner, when either HUVEC [a] or HUA-EC [b] were incubated for 24 h with increasing amounts of blackseed oil.
The observation that endothelial cells of different sites (HUVECs and HUA-ECs) respond similarly to blackseed oil confirms the universality of this pattern across different vascular tissues.
The results showed that blackseed oil decreases the fibrinolytic potential of the human fibrosarcoma cell line (HT1080) in vitro, implying that inhibition of local tumor invasion and metastasis may be one such mechanism.
The historical tradition of blackseed use in medicine is substantial.
Exposure to the volatile oil obtained from blackseed altered the cellular expression of specific polypeptides in Jurkart T lymphoma cells, suggesting that changes in polypeptide expression might play a role in the biological activities attributed to blackseed (Hailat et al.
Blackseed oil was dissolved in DMSO at a concentration of 10-200 mg and stored at -80[degrees]C.
Effects of blackseed oil on the release of t-PA, u-PA and PAI-1 antigen
Worthen DR, Ghosheh OA, Crooks PA (1998) The in vitro anti-tumor activity of some crude and purified components of blackseed
, Nigella sativa L.