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  • noun

Synonyms for agonist

the principal character in a work of fiction


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someone involved in a contest or battle (as in an agon)

a muscle that contracts while another relaxes

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(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

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References in periodicals archive ?
Long-acting beta-2 agonists are used for the chronic maintenance of asthma, not for acute attacks, and are often administered in a fixed-dose combination with an inhaled corticosteroid, such as Advair Diskus (salmeterolgiuticasone).
More recently, long-acting beta-2 agonist drugs (LABA) salmeterol and eformoterol have gained popularity in the management of asthma that is not well-controlled with short-acting beta agonist and inhaled corticosteroid therapy (ICS).
Beta-2 agonists were shown to increase the cardiac repolar-izing current and have previously shown to increase QT dispersion (QTd) which is thought to represent regional differences in ventricular repolarization (1-4).
One approach is to treat this patient with a long-acting beta-2 agonist such as salmeterol or formoterol around the clock.
The beta-2 agonist use was reduced by 95%, and the corticosteroid inhaler was reduced by 92%.
Overall, the results indicate that daily use of an inhaled short-acting beta-2 agonist was associated [odds ratio (OR) = 1.
The report compared the use of the newer anti-inflammatory drugs with the more conventional asthma drugs, such as theophylline and the newer bronchodilators known as beta-2 agonists.
4 The World Short-Acting Beta-2 Agonist (SABA) Market: Revenues ($bn) and Market Shares (%) by Leading Drugs, 2012 Table 4.
2 Key Products Marked Share (%) Within the Beta-2 Agonist Category, 2008
They also have a short-acting beta-2 agonist available for quick relief when necessary.
A full trial and documented compliance with inhaled high-dose corticosteroids and long acting Beta-2 agonists in addition to leukotriene receptor antagonists, theophyllines, oral corticosteroids and Beta-2 agonist tablets and smoking cessation where applicable.
Pearl is rapidly advancing a pipeline of products including PT003, an inhaled, fixed-dose combination bronchodilator product comprised of a long-acting muscarinic antagonist (LAMA) and a long-acting beta-2 agonist (LABA) delivered via a metered dose inhaler (HFA MDI); and PT010, a triple-combination product that combines the LAMA and LABA components of PT003 with an inhaled corticosteroid (ICS) for twice-daily administration from an HFA MDI for the treatment of severe COPD.
announced plans to make 11 presentations at upcoming medical meetings to report clinical and product development information pertaining to PT003(GFF MDI), a proprietary, fixed-dose combination of glycopyrrolate (GP), a long-acting muscarinic antagonist (LAMA) and formoterol fumarate (FF), a long-acting beta-2 agonist (LABA).
The company has also successfully combined a nanogram-level GP dose with a previously established therapeutic dose of formoterol fumarate (FF), a long-acting beta-2 agonist (LABA).