perfringens isolates were resistant to benzylpenicillin
and clindamycin, but all were sensitive to cefoxitin, metronidazole, chloramphenicol and amoxicillin-clavulanate.
Regular attendance should be encouraged for follow-up assessments and to receive benzathine benzylpenicillin
USUALLY an antibiotic called benzylpenicillin
, which can stop the bacteria spreading.
Initially, she had been treated with cefuroxime, but the therapy was consequently changed to benzylpenicillin
f AMX Survivor, n = 16 0 ([double dagger]) 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10 - 11 - 12 - 13 - 14 - 15 - 16 - Nonsurvivor, n = 11 1 (9) ([double dagger]) 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10 - 11 + Total, n = 27 1 (4) * CLI, clindamycin; CIP, ciprofloxacin; BPC, benzylpenicillin
(penicillin G); FLUX, flucloxacillin; MTZ, metronidazole; CRO, ceftriaxone; GEN, gentamicin; VAN, vancomycin; MEM, meropenem; TZP, piperacillin/tazobactam; AMC, amoxicillin/clavulanic acid; AMX, amoxicillin; +, antibacterial drug administered; -, antibacterial drug not administered.
Water-soluble drugs, such as gentamycin, furosemide, methotrexate, benzylpenicillin
and digoxin, are therefore excreted unchanged in the urine because they do not need to undergo biotransformation to increase their water solubility.
8 125 125 Benzathine benzylpenicillin
125 250 250 250 Amnicillin 62.
5 mM) + + Benzylpenicillin
potassium + + (10,000 IU) Ca[Cl.
Reactivity to beta-lactam antibiotics was found in five cases, with two patients demonstrating sensitisation to cephalothin, two to benzylpenicillin
and one to both agents.
max]) for drugs administered by the intramuscular route is comparable for infants, children, and adults for aminoglycosides, ampicillin, and carbenicillin [11-14], whereas preterm infants exhibit delayed absorption of chloramphenicol, rifampicin, cephalexin, cephaloridine, and benzylpenicillin
Prior Information Notice: Delivery antibacterial agents for systemic use - cefazolin, ampicillin and benzylpenicillin
9]/L) Creatinine 385 488 (60-125 nmol/L) Albumin (30-45 g/L) 24 23 Characteristic Patient 3 Age, y/sex 60/M Comorbidities Hepatitis C, left femoral artery pseudoaneurysm Route of infection Injected into left femoral artery Site affected when Pulsatile mass at left patient sought groin area; no edema or treatment swelling evident Surgery On hospital d 1, surgery performed to repair left femoral artery pseudoaneurysm and debridement; further debridement performed at d 19 Anthrax testing results Culture Blood and tissue cultured on admission negative Serologic Positive PCR Negative Initial antibiotic Clindamycin, ciprofloxacin, drugs flucloxacillin, benzylpenicillin
, metronidazole Outcome After first surgery on hospital d 1, continued broad- spectrum antibiotic drugs for 10 d.