The eye drop preservative benzalkonium chloride
potently induces mitochondrial dysfunction and preferentially affects LH0N mutant cells.
Pharmacological modification of the epithelial permeability by benzalkonium chloride
in UVA/Riboflavin corneal collagen cross-linking.
Only the strong irritant benzalkonium chloride
was found to be false-positive regarding CD54.
Proparacaine contains benzalkonium chloride
and EDTA as preservative agents, and both compounds also function as drug penetration enhancers.
(BAC), the most commonly used preservative in anti-glaucoma eye drops, is largely responsible for the toxicity.
Compared with the cmc and cmc of benzalkonium chloride
including dodecyldimethylbenzyl ammonium chlorides (BC12), tetradecyldimethylbenzyl ammonium chlorides (BC14) and hexadecyldimethylbenzyl ammonium chlorides (BC16) that reported by Farias and Gracia, et al [22-24], we could know the surface activity of ADMDHAC in aqueous solution was the best one among BC12, BC14, BC16 and ADMDHAC.
Although it may appear that there is some variation, all these products contain the same concentrations of the active ingredient, latanoprost, and the preservative, benzalkonium chloride
Topical antiseptics Dermatological diseases Benzalkonium chloride
6,7) Its preservative, benzalkonium chloride
, induces cell growth arrest and death in conjunctival epithelium, as well as cytotoxicity to corneal epithelial cells.
The presence of benzalkonium chloride
in a commercial product designated for internal and external use by humans is troubling in light of its toxicity and allergenicity.
Other problematic ingredients in many conventional mouthwashes include sodium lauryl sulfate, polysorbate, cetylpyridinium chloride and benzalkonium chloride
, all which have been shown to be toxic to organisms in the aquatic environments where these chemicals end up after we spit them out.
is an organic compound with antiseptic properties, while triclosan is a chlorophenol ingredient currently mired in controversy.
A large body of evidence has indicated that ocular preservatives, particularly benzalkonium chloride
(BAK), impair surface tissues of the eye leading to inflammation, dry eye and other issues," explained Penny Asbell, M.
Use of household cleaning products that contain benzalkonium chloride
may decrease the susceptibility of bacteria to other antimicrobial ingredients in cleaning products and increase their resistance to antibiotics, according to the results of a randomized, double-blind study.
This is the first randomized intervention study to assess the relationship between two biocidal ingredients found in household cleaning products benzalkonium chloride
(BZK) and triclosan--and antibiotic resistance in the household setting, Allison E.