3) Histologic findings of proliferative myositis include two primary features: infiltration of the muscle with large basophilic
giant cells that resemble ganglion cells and proliferative fibroblasts primarily affecting the interfascicular connective tissue.
The ossicles show basophilic
centre with a periphery of pink rim.
The cells are described as uniform, with round to oval or basaloid morphology, scant to moderate eosinophilic cytoplasm, pale basophilic
nuclei, and visible but not prominent nucleoli (1-4, 6, 7, 12).
Spleen tumor revealed large number of intensive lymphoblast with a consensus morphological structure, less cytoplasm, basophilic
, enlarged thick dye nucleus and densely meshed chromatin (Fig.
9) Classic pulmonary lesions of GPA include large geographic necrotizing granulomas that show a basophilic
appearance (Figure 1, C).
Clinically insignificant, fine basophilic
stippling may be associated with polychromasia/accelerated erythropoiesis/reticulocytosis.
Peripheral Blood Smear Examination (Under Leishman Stain) Hypochromia Target Cell Microcytosis Polychromasia Anisocytosis Normoblast Poikilocytosis Basophilic
Stippling Spherocytes c.
The nucleus is basophilic
, contains delicate granular chromatin and one, two or three nucleoli that are more intensely basophilic
The yeast were round to oval, 15-33 [micro]m in total diameter, with poorly staining central portions (5-12 pm in diameter) surrounded by a pale acidophilic or basophilic
capsule (5-21 [micro]m thick), which stained positively with a mucicarmine stain.
Spheroid type 2, considered to develop from type 1, appeared more basophilic
in staining, and was fully encapsulated with a fibrous connective sheet and a layer of cells with flat nuclei.
Histologically, pilomatrixoma is an encapsulated lesion comprising small, solid basophilic
cells and pathognomonic ghost (shadow) cells (figure 3).
The peripheral smear examination showed anisopoikilocytosis with macrocytes, microcytes, schistocytes, target cells, basophilic
stippling, and hypochromia of RBCs.
Myeloid neoplasms with t(5;12) and ETV6-ACSL6 gene fusion are rare, poorly characterized hematologic neoplasms with an aggressive clinical course characterized by eosinophilic and/or basophilic
The neoplastic cells varied from spindle to pleomorphic with basophilic
cytoplasm, hyperchromatic nuclei, and multiple nucleoli (Fig 2B).
The staining of the nucleus is basophilic
with darker regions representing condensed chromatin (Lucas and Jamroz, 1961).