Of the ten positive samples, four exhibited a focal positive staining, whereas six exhibited a uniform staining of the entire basal layer
Nevertheless, few studies have been directed to evaluate the nuclear size and its variability in the preneoplastic epithelium of PIN, although some authors have suggested that the cytologic atypia and nuclear pleomorphism were more remarkable in the basal layer
in comparison with the apical or columnar stratum of PIN lesions (Epstein, 1994).
5), correlates with the lowermost, argillaceous basal layer
of the Jogeva Beds in the Nurmekund Formation (Figs.
It's made up of cells which begin their life plumped full of moisture in the basal layer
, then dry out and harden as they reach the surface to form an effective water and germ barrier.
So the question becomes: Does gray hair actually pipe in cancer-causing ultraviolet light to the basal layer
, enabling the light to bypass the damage-deflecting mechanisms of the scalp?
By 2002 drilling confirmed this premise with the discovery of a basal layer
of enriched sulphides containing platinum, palladium, nickel and copper.
A proliferation of dendritic melanocytes (Figure 5, A) and mature sebaceous cells (Figure 5, B) were easily seen along the basal layer
of the cyst.
The classic appearance is a "sawtooth" pattern to the rete, with a hydropic degeneration of the basal layer
(figures 1 and 2).
Cells of the basal layer
(basal cells) adhere to the basement membrane, which separates the dermis from the underlying dermis.
HBD-3 is only found in the basal layer
where oral cancers grow and is present when the cancerous tumour progresses.
In adult exoskeletal elements three layers can be distinguished: (1) the upper layer of the orthodentine of ridges and tubercles, (2) the middle spongiose layer, and (3) the denser basal layer
Fas-ligand (FasL), a member of the tumor necrosis superfamily, which is preferentially expressed in the basal layer
of the skin epidermis, is a key surveillance molecule involved in the elimination of sunburn cells, but also in the prevention of cell transformation.
The study, conducted in mouse models of oral mucositis, showed that NU206 regenerated basal layer
epithelial cells and accelerated cell repair by stimulating the Wnt pathway, a signaling pathway that is critical for cell growth and differentiation during homeostasis and pathogenesis.
The overlying epidermis has elongated rete ridges and a hyperpigmented basal layer
Cutaneous injuries can result from the direct effects of radiation, especially on the highly radiosensitive basal layer