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In one series, S pneumoniae (SP) was the second most common isolate from children younger than 2 years with bacterial arthritis.
Included in this group is Osteoarthritis, Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, Lyme Disease Arthritis, Infectious and Bacterial Arthritis to name a few.
These SAEs included angioedema (swelling beneath the skin) and urticaria (hives) in one patient and varicella (chickenpox) and bacterial arthritis.
Schattner A, Vosti KL: Bacterial arthritis due to beta-hemolytic streptococci of serogroups A,B,C,F, and G.