13) Whereas AQP4 has a widespread astrocytic
pattern, AQP1 has a more restricted localization.
HuVV mice were examined for evidence of astrocytic
Global patterns of glial changes in the brain indicate that females mount a transient astroctyic response--but no microglial response--to CAPs exposure, whereas males show both astrocytic
and microglial dysfunction that persists into early adulthood.
Using light microscopy, histological features such as vacuolation, spongiform changes, astrocytic
gliosis and amyloid plaques can generally be observed.
Among gliomas, glioblastoma is the most malignant astrocytic
primary brain tumor that represents 20-30% of all primary intracranial tumors (2).
12) Retinal tumours such as astrocytic
hamartoma, combined hamartoma of the retinal pigment epithelium (RPE) and retina, and retinal capillary haemangioma can rarely affect people with NF-1.
Interobserver reproducibility of MIB-1-labeling index in astrocytic
tumors using different counting methods.
The microscopic neuropathology consistently includes the distinctive finding of dense tau neurofibrillary tangles and astrocytic
tangles throughout the frontal and temporal cortices in a superficial patchy distribution, as well as throughout the rest of the brain.
To create the different types of astrocytes used in the experiment, researchers isolated human glial precursor cells and exposed these precursor cells to two different signaling molecules used to instruct different astrocytic
cell fate - BMP (bone morphogenetic protein) or CNTF (ciliary neurotrophic factor).
These tumors develop most commonly in the cerebrum and represent 35% of all astrocytic
School of Medicine, Atlanta) jointly contributed the introduction and the following chapters: normal brain histopathology (Brat), astrocytic
and ligodendroglial tumors (Brat and Perry), neuronal and glioneuronal neoplasms (Brat), meningiomas (Perry), melanocytic neoplasms of the central nervous system, other glial neoplasms (both by Brat) and therapy-associated neuropathology, and familial tumor syndromes (both by Perry).
VP and OX neurons often lie adjacent to one another, separated only by fine astrocytic
Ischemic injury to the central nervous system causes cellular activation and disintegration, leading to release of cell-type-specific proteins such as myelin basic protein (MBP),  glial fibrillary astrocytic
protein (GFAP), the calcium-binding protein S100B, and neuron-specific enolase (NSE).
The membrane fusion process in astrocytic
exocytosis occurs when sufficient levels of intracellular calcium are present in the astrocyte.
These neuroblasts in the striatum formed elongated chain-like cell aggregates similar to those in the normal SVZ, and these chains were closely associated with thin astrocytic
processes and blood vessels28.